Project Grant R43GM125412

This $100,000 National Science Foundation Technology, Innovation, and Partnerships grant funds the development of tunable porosity aerogel for wound care dressings at The University of Akron from July 1, 2022 to June 30, 2023. The project aims to create a novel bio-based aerogel dressing that could help heal patients with chronic wounds faster by requiring fewer dressing changes. Aerogels' high porosity, surface area and moisture balance properties may create an incubator-like wound healing...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $300,000 to Ionic Pharmaceuticals, LLC to develop a novel quorum sensing inhibitor-based wound dressing to treat second-degree burn wound infections caused by methicillin-resistant Staphylococcus aureus (MRSA). The key objectives are to: 1) optimize the formulation of the W-hydroxyemodin-loaded hydrogel-based wound...

This $275,000 Project Grant awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development and validation of an aerogel-based biomaterial wound dressing platform by Auxilium Health, Inc. The proposed wound dressing combines fluid management, biofilm prevention, and rapid infection detection capabilities to improve the management of chronic wounds, surgical sites, and burns. The project aims to...

This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $349,345 to Fesariustherapeutics Inc. to develop and demonstrate the feasibility of an advanced dermal regeneration scaffold called Dermisphere for the management of acute major burn wounds. Dermisphere aims to regenerate dermis in full-thickness skin loss wounds significantly faster than current market-leading dermal replacement...

This $250,000 National Science Foundation project grant supports the development of a microneedle-mediated adaptive phototherapy wound dressing by the University of South Florida from October 1, 2022 to November 30, 2024. The dressing integrates self-diagnosis and treatment tailored to wound conditions without external electronics or medical professionals. Microstructured microneedles act as optical waveguides to deliver localized blue or red light therapy at wound sites, changing wavelength...

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Gelsana Therapeutics Inc., a woman-owned small business and HUBZone certified corporation, a $649,984 Project Grant (CFDA 93.847) on September 5, 2024. The grant supports the development of Provasliex Gel, a zwitterionic hydrogel that delivers controlled release of platelet-derived growth factor (PDGF) to promote wound healing and manage inflammation in diabetic foot ulcers. The goal is to demonstrate...

This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $2,433,408 to Global Biomedical Technologies LLC to develop and validate an innovative adhesive acrylic negative pressure wound therapy (NPWT) drape. The key objectives are to 1) compare the performance of the "Comfort Release" NPWT drape developed...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) grant of $305,000 awarded to Therapeutic Bandage Products, Inc. will fund the development of an advanced microneedle bandage for treating diabetic foot ulcers. The microneedle patch is designed to deliver a combination of therapeutic agents, including an antibiotic, an agent to prevent biofilm formation, and a chemokine to activate the immune system....

This National Science Foundation (NSF) Engineering Research Initiation (ERI) Project Grant, awarded by the NSF Division of Chemical, Bioengineering, Environmental, and Transport Systems, aims to develop a new type of bioadhesive using hydrophilic polydopamine (HPDA) to improve healing of inner meniscus tears. The project will synthesize and characterize HPDA, then incorporate it into hydrogel-based bioadhesives to be tested in vitro. The specific objectives are to understand the adhesion...

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Lynntech Inc. a $687,416 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop a cutaneous gel that can controllably deliver a small molecule therapeutic to effectively treat diabetic foot ulcers (DFUs). The project aims to (1) prepare and characterize a preferred gel formulation for controlled delivery, (2) further elucidate the therapeutic's...