Project Grant R43AI183989
Award Date
7/1/24
Completion Date
6/30/25
Dollars Obligated
$300K
Federal Agency
National Institute of Allergy and Infectious Diseases
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Massachusetts, USA
Similar Awards
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant totaling $392,634 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Wisconsin-Madison on May 13, 2025. The funding supports the development of a novel broad-spectrum nanoimmunotherapeutic approach for combating multidrug-resistant (MDR) bacterial infections, particularly those caused by the ESKAPE pathogens. The project aims to design, fabricate, and optimize a...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $298,530 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Scientific Horizons Consulting LLC in Irvine, CA. The grant supports the development of a novel antibiotic delivery system using cyclodextrin-based metal-organic frameworks (CD-MOFs) to improve the pulmonary administration and treatment of non-tuberculous mycobacterial (NTM) lung infections. Key innovations include...
This $840,462.15 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support research to understand the mechanisms of Staphylococcus epidermidis biofilm formation on medically relevant surfaces. The goals are to: 1) establish the structural and biophysical rules governing S. epidermidis protein binding to polymethylmethacrylate (PMMA) surfaces, 2) develop a novel PMMA surface...
The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded a $288,360 Project Grant to Biological Mimetics, Inc. to develop a novel vaccine candidate against multi-drug resistant Acinetobacter baumannii (MDR-AB). The project aims to (1) identify and characterize key immunogenic components of MDR-AB that can elicit protective immunity, (2) develop a prototype vaccine formulation, and (3) conduct...
The National Institute of General Medical Sciences (NIGMS) awarded a $405,015 Project Grant under the Biomedical Research and Research Training Program (CFDA 93.859) to Inter American University of Puerto Rico, Inc. (IAUPR) to investigate the mechanism of action of antibacterial synthetic unsaturated fatty acids against methicillin-resistant Staphylococcus aureus (MRSA). The central goal of this 3-year research project is to define the mechanisms by which synthetic unsaturated fatty acids,...
This $126,174 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to investigate the local immune response in human skin during bacterial infections. The project aims to use an innovative skin-on-a-chip model to provide mechanistic insights into the migration and granulopoiesis (production of neutrophils) of hematopoietic stem and progenitor cells in the skin in...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $165,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Surgical Infection Society Foundation For Education And Research. The grant will fund the planning and organization of a multi-center, randomized clinical trial to test the hypothesis that clinicians can use serial C-reactive protein (CRP) measurements to individualize the duration of antimicrobial therapy for...
The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded a $474,363 Project Grant to Rowan University to develop novel, daptomycin-inspired antimicrobial peptides using non-canonical amino acids. The goal is to create peptide molecules that mimic daptomycin's key antimicrobial properties of calcium binding and lipid membrane disruption, while improving resistance to host degradation and optimizing the...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $684,206 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Maryland, Baltimore to develop a novel nanoparticle-based immunotherapy for the treatment of sepsis. The objectives of this 5-year research project are to: 1) evaluate the immunomodulatory properties of a focused set of nanoparticles to achieve maximal therapeutic efficacy in a sepsis model, 2) identify...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training Program (CFDA 93.859) supports the development of Dermisphere, an advanced dermal regeneration scaffold product by Fesariustherapeutics Inc. The $349,345 award, with a period of performance from September 1, 2024 to August 31, 2025, aims to demonstrate the feasibility of using Dermisphere to manage acute major burn wounds. The product is intended to...