This $100,000 Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program will support the development of an advanced wound care technology at Florida International University. Specifically, the university will create a bandage-integrated platform that provides feedback-mediated wound therapy to enable personalized care. The conformable platform is designed to non-invasively monitor multiple wound biomarkers in spatial detail and then apply targeted...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award provides $275,000 to Biodynamik, a for-profit organization, to develop an innovative implantable device for treating diabetic foot ulcers (DFUs). The project aims to design and test a low-profile, implantable "transverse tibial transport" device that uses mechanical distraction to stimulate soft tissue growth and improve blood flow, providing a new treatment option for...
This $250,000 National Science Foundation project grant supports the development of a microneedle-mediated adaptive phototherapy wound dressing by the University of South Florida from October 1, 2022 to November 30, 2024. The dressing integrates self-diagnosis and treatment tailored to wound conditions without external electronics or medical professionals. Microstructured microneedles act as optical waveguides to deliver localized blue or red light therapy at wound sites, changing wavelength...
This $305,000 SBIR Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of a novel mammalian cell-based nano-biological coating for implantable medical devices. The project aims to create a biocompatible and antimicrobial coating to inhibit biofilm formation and protect against bacterial infections, including antibiotic-resistant strains, on orthopedic implants. Key technical objectives include...
The National Science Foundation Division of Industrial Innovation awarded a $256,000 Project Grant to develop an automatic debridement device from August 1, 2021 through March 31, 2022.
This Small Business Innovation Research Phase I award under the Engineering (47.041) program will support the creation of a product to automatically remove dead, damaged, or infected tissue. The NSF Directorate for Engineering seeks to foster innovation and excellence in engineering research, consistent with...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $687,416 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Lynntech Inc. to develop a cutaneous gel for the controlled delivery of a small molecule therapeutic to treat diabetic foot ulcers (DFUs). The project aims to (1) prepare and characterize the preferred gel formulation, (2) further elucidate the mechanism of action, and (3) evaluate the...
This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $275,000 to Auxilium Health, Inc. to develop and validate an aerogel-based biomaterial wound dressing. The proposed dressing aims to promote tissue regeneration, block microbial infiltration, absorb wound fluid, and provide rapid visual indication of infection. The project seeks to optimize the aerogel's pore structure for biofilm...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $335,342 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Adepthera LLC, a for-profit limited liability company. The purpose of this award is to develop a novel gel therapy for accelerating wound healing in diabetes patients. The project aims to identify an optimal gel formulation that provides sustained and localized treatment, and investigate...
This $1,000,000 Cooperative Agreement award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports the productization, clinical validation, and quality/regulatory activities for Empo Health, Inc.'s in-home diabetic foot imaging bathroom scale system. The project aims to advance the design, engineering, and manufacturing of this novel remote monitoring solution to detect early signs of foot ulcers in diabetic patients, a condition...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) SBIR Phase I project awarded $275,000 to Islex Therapeutics, LLC to develop antibody therapeutics for the treatment of Stage 3 type-1 diabetes (T1D). The project aims to harness the synergistic effects of autoimmune protection, insulin supplementation, and targeted delivery of mitogenic drugs to the pancreatic islet to restore beta-cell function in patients with severe beta-cell loss. The research...