Project Grant R43EY037637
- This federal Project Grant award of $598,108 from the National Eye Institute (CFDA 93.867 Vision Research) supports the development of innovative ophthalmic imaging technologies and novel objective, quantifiable functional biomarkers for cone photoreceptors. The primary aims are to: 1) Develop next-generation optical coherence tomography (OCT) technologies to enable functional photoreceptor imaging over a wide retinal area and at high topographical resolution; and 2) Develop novel objective,...
- The National Eye Institute (NEI) awarded Kineolabs, Inc. a $300,001 Project Grant under the Vision Research program (CFDA 93.867) to develop a portable, low-cost line-scan swept-source optical coherence tomography (LS-SS-OCT) imaging system. The objective is to use this LS-SS-OCT technology for early detection and monitoring of age-related macular degeneration (AMD), diabetic retinopathy, and other eye diseases. The project aims to make OCT imaging more affordable and accessible to reduce the...
- This $147,486 federal project grant awarded on April 1, 2025 by the National Eye Institute (CFDA 93.867 - Vision Research) will support research to characterize retinal function using adaptive optics scanning light ophthalmoscopy (AOSLO) based psychophysics and optoretinography. The key objectives are to: 1) Examine how disruptions in foveal anatomical specializations impact visual function using AOSLO-based tools, and 2) Improve understanding of the intensity-based optoretinography (IORG)...
- This Project Grant award from the National Eye Institute's Vision Research program (CFDA 93.867) provides $179,964 to the University of California, Irvine (UCI) to develop innovative biomarkers for optic neuropathies using deep learning-based analysis of optical coherence tomography (OCT) imagery. The project aims to overcome limitations of current OCT-based diagnostics by employing advanced computational techniques like deep learning, neural fields, and geometric modeling to enhance the...
- The National Eye Institute (NEI) awarded a $256,296 Project Grant (CFDA 93.867 - Vision Research) to The General Hospital Corporation (Massachusetts General Hospital) to develop new "Auto-Sensing, Instantaneous Adaptive Ranging Optical Coherence Tomography (OCTA)" technology. This technology aims to expand the imaging depth range of OCTA systems, enabling improved visualization of the critical peripheral retinal microvasculature. The project will leverage advances in integrated...
- The National Eye Institute (NEI) awarded a $673,747 Project Grant to New York University (NYU) for the "Visible-to-Near-Infrared Spanning Optical Coherence Tomography for Retinal Imaging at the Half-Micron Scale" research project under the NEI's Vision Research program (CFDA 93.867). The grant aims to develop advanced optical coherence tomography (OCT) techniques to enable more accurate in vivo measurement and localization of macular pigments and retinal pigment epithelium melanosomes,...
- This $231,000 Project Grant award from the National Eye Institute (NEI), under the federal Vision Research program (CFDA 93.867), will fund the development of a generalized deep learning platform to improve the objectivity, reproducibility, and accuracy of quantifying and assessing experimental autoimmune uveitis (EAU) - a valuable animal disease model for studying human uveitis. The project aims to generate high-quality, well-annotated multi-modal datasets from three independent research...
- This is a Cooperative Agreement award from the National Eye Institute (NEI), part of the U.S. Department of Health and Human Services, under the Vision Research federal grant program (CFDA 93.867). The $791,994 award, which began on September 1, 2025, supports the development of a next-generation ophthalmic microscope with integrated optical coherence tomography (OCT) imaging capabilities. The project aims to overcome limitations of current ophthalmic surgery microscopes by enabling more...
- This Cooperative Agreement award from the National Eye Institute (CFDA 93.867 - Vision Research) provides $583,247 to Panluminate Inc., a woman-owned small business, to develop a novel microscopy technology called Pan-Optix. The Pan-Optix system combines two advanced imaging techniques, Pan-Expansion Microscopy (Pan-EXM) and FLASH-PAINT, to enable multi-scale, 3D mapping of molecular markers in retinal tissue at the cellular and ultrastructural level. The project aims to (1) validate the Pan-EXM...
- The Project Grant award from the National Eye Institute (CFDA 93.867 Vision Research) supports the development of an accurate, non-invasive, and automated 24-hour intraocular pressure (IOP) monitoring device. The overarching goal is to create a wearable IOP monitor that can improve the clinical management of glaucoma, the leading cause of irreversible blindness. The $713,964 award will fund research activities over a 5-year period from March 2025 to February 2030 at the University of California,...
This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) aims to develop and validate a novel Adaptive Optics Optical Coherence Tomography (AO-OCT) system tailored for high-resolution, wide-field retinal imaging in small animal models, specifically mice. The $305,000 project, awarded on September 1, 2025, with an expected completion date of August 31, 2026, has two key objectives: Develop and optimize a portable AO-OCT system with enhanced imaging capabilities using a customized contact lens. This will involve designing and fabricating an optical system that integrates adaptive optics with a 150-degree wide-field view and 2-micron resolution. Validate and optimize the AO-OCT system using wild-type mouse models, first with a phantom eye model and then through in vivo testing. This validation process will demonstrate the system's reliability, reproducibility, and ability to capture high-quality, high-resolution retinal images. The project is being conducted by The Aird (UEI: YYG5ZNMLABK9) and will leverage collaboration with researchers at UC Davis. The anticipated outcomes include advancing diagnostic technologies to improve understanding of ocular diseases and neuronal dynamics, contributing to the development of better strategies for retinal disorders.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $305.0k | 8/28/25 |