Project Grant R43DK139914
Award Date
7/15/24
Completion Date
6/30/25
Dollars Obligated
$663K
Federal Grant Program
93.847
Assistance Type
Project Grant
Place of Performance
Bellefonte, PA 16823, USA
Similar Awards
This $337,284 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will support the development of a novel "Precision-Cut Bladder Slice" (PCBS) technology at Boston Children's Hospital. The goal is to enable quantitative assessment of bladder smooth muscle contraction, relaxation, and stiffness in both healthy murine and human tissues, while...
This $725,420 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to develop and validate an optimized allysine-targeted positron emission tomography (PET) probe for non-invasively detecting and quantifying renal fibrosis. The project, with a period of performance from September 2024 to June 2029, will accelerate the clinical translation of this...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $324,678 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Lumina Medical LLC. The grant supports the development of an innovative motorized, girth-adjustable anal dilator device designed to improve patient adherence to anal dilation treatment for conditions such as anismus and anal stenosis. Key project objectives include transitioning to a medical...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $708,138 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the Ann & Robert H Lurie Children's Hospital of Chicago. This 4-year grant, awarded from December 2024 through November 2028, will support the development of a biomechanocompatible small molecule-releasing scaffold for bladder augmentation. The project aims to create an alternative to...
This $628,012 Project Grant award from the National Institute of Neurological Disorders and Stroke (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) is funding the development and validation of a novel minimally invasive electrode system to better isolate the posterior tibial nerve for the treatment of overactive bladder (OAB). The University of Wisconsin System is the prime awardee, and they are collaborating with sub-awardees Neuronoff Inc. to...
This $345,650 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research by Reshape Lifesciences Inc., a small business joint venture, to develop an innovative "Diabetes Targeted Dual Neuromodulation Therapy (TDN Therapy)." The key objectives are to: Determine the minimum effective current amplitude for the high-frequency...
This $206,132 Project Grant awarded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) aims to develop a wireless, battery-free bioelectronic implant that can provide autonomous closed-loop neuromodulation to manage detrusor sphincter dyssynergia (DSD) in individuals with spinal cord injury. The project will fabricate and validate the implant, which will...
This $543,826 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to develop novel bioengineered regenerative medicine solutions for vascular tissue engineering. The research project, conducted at the University of Pittsburgh, focuses on understanding the mechanisms behind injury-inducible, in vivo vasculogenic reprogramming using a...
This $548,830 Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which oversees the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant was awarded to Nephsmart LLC, a for-profit limited liability company located in Little Rock, Arkansas, to develop and test a point-of-care device that can predict the future development of severe acute kidney injury (AKI) based on detecting specific protein cleavage...
Vivonics Inc., a medical technology company based in Massachusetts, received a $331,455 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) to develop a near-infrared layered imaging system called NIR-LITH. This system aims to provide objective, three-dimensional hemodynamic mapping of diabetic foot ulcers and surrounding tissue with 1 mm depth resolution, improving clinicians' ability to assess wound healing potential and make more accurate...