Project Grant R43DK137630

Award Date 9/11/23
Completion Date 8/31/24
Dollars Obligated $331K
Federal Grant Program
93.847
Assistance Type
Project Grant
Place of Performance
Massachusetts, USA
Similar Awards
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $425,176 Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) to Eden Medical, Inc. to develop the "Smart Foot Mat" (SFM). The SFM is an in-home appliance designed to help prevent diabetic foot complications by allowing diabetic patients to monitor their foot oximetry and temperature on a daily basis. The grant funding will support the development of this novel...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $268,377 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The University of North Texas Health Science Center at Fort Worth. The grant aims to develop and evaluate a novel device using high-frequency, low amplitude vibration (HFLAV) to accelerate healing of stage 2 diabetic foot ulcers (DFUs) and improve patient quality of life. Key objectives...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $1,136,156 Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) to Visionquest Biomedical Inc., a small disadvantaged and veteran-owned business located in Albuquerque, New Mexico. The funding will support the development of an integrated smartphone-based system for the quantitative detection of diabetic peripheral neuropathy (DPN) in underserved communities. The project...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $712,628 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Barron Associates, Inc. in Charlottesville, Virginia. The purpose of this Phase I SBIR grant is to develop and validate the SoleSaver System, a sensor-enabled foot-worn garment that continuously monitors multiple aspects of foot health, including pressure, temperature, and gait, to enhance...
This Project Grant award of $687,416, provided by the National Institute of Diabetes and Digestive and Kidney Diseases under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports the development of a cutaneous gel to controllably deliver a therapeutic with an intriguing mechanism of action to effectively address impaired wound healing in diabetic foot ulcers (DFUs). The project aims to (1) prepare, characterize, and select a preferred gel formulation...
This Project Grant award of $305,000 from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of an advanced wound care product for treating diabetic foot ulcers. The product utilizes a patented microneedle patch design to deliver three therapeutic agents that disinfect the wound, prevent bacterial biofilm formation, and activate the immune system to promote healing. Initial work will be conducted using skin tissue...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Gelsana Therapeutics Inc. a $649,984 Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) on September 5, 2024. The purpose of this grant is to support the development of Provasliex Gel, a zwitterionic hydrogel that delivers controlled release of platelet-derived growth factor (PDGF) to address impaired wound healing associated with diabetes. The goal is to demonstrate the...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Emory University a 5-year, $555,034 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant will fund the "Comprehensive Assistance and Resources for Effective Diabetic Foot Navigation (CARE-D-FOOT-NAV)" randomized controlled trial. The project aims to assess the effectiveness of a patient navigator program in improving diabetic foot ulcer...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) project aims to develop a novel implantable system that leverages distraction osteogenesis as a treatment for diabetic foot ulcers (DFUs). The $295,000 award, effective from December 15, 2024 to August 31, 2025, supports the design and development of a low-profile implantable transverse tibial transport device. This device integrates an active mechanical...
This $205,000 project grant from the National Institutes of Health's National Institute on Aging will fund research into the pathomechanics of diabetic foot ulcers at The University of Texas Southwestern Medical Center over a 12-month period. The research aims to identify more accurate markers and marker combinations for foot ulceration risk in patients with diabetic neuropathy and a history of prior ulcers. Using specialized equipment, the study will quantify two primary ulcer-causing...

Vivonics Inc., a medical technology company based in Massachusetts, received a $331,455 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) to develop a near-infrared layered imaging system called NIR-LITH. This system aims to provide objective, three-dimensional hemodynamic mapping of diabetic foot ulcers and surrounding tissue with 1 mm depth resolution, improving clinicians' ability to assess wound healing potential and make more accurate treatment decisions. The project involves enhancing a first-generation prototype to improve depth discrimination capabilities, developing depth discrimination algorithms and phantom testing, and evaluating the system with 30 diabetic foot ulcer patients at the University of Texas Southwestern Medical Center. This work seeks to address the lack of objective metrics for monitoring wound progress, which can lead to poor prediction of healing or amputation level survival even among experienced clinicians.

Generated 7/16/24, 3:16 AM