Project Grant R43DA051279

Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded Biomotivate LLC a $613,744 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and evaluate the PEACE Platform (Personalized Evocative Audiovisual Content for Everyone), a precision medicine tool designed to support emotional regulation and resilience in individuals with opioid use disorders (OUDs). The platform combines generative artificial intelligence, predictive analytics,...

This Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) provides $844,475 to the University of Alabama at Birmingham (UAB) to test a bundled intervention aimed at increasing treatment uptake for patients with opioid use disorder (OUD) and nonfatal opioid overdoses after emergency department (ED) discharge. The proposed intervention combines telehealth, peer support, buprenorphine prescribing, and linkage to...

The National Institute on Drug Abuse (NIDA) awarded a $2,729,018 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the University of Rhode Island. The purpose of this 2-year award, with a start date of September 15, 2024, is to rigorously develop and evaluate a mobile health intervention for adults with co-occurring opioid use disorder (OUD) and post-traumatic stress disorder (PTSD) during community re-entry after residential OUD treatment. The proposed mobile app...

This Project Grant award of $451,000.00 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to leverage natural language processing (NLP) and mixed methodologies to identify and classify medication treatment information needs of individuals with opioid use disorder (OUD) on the social media platform Reddit. The project has three key objectives: 1) Identify buprenorphine- and methadone-related treatment information needs...

Federal Grant Award Summary The National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded the University of Florida a Project Grant of $779,327 (awarded August 15, 2025, with completion targeted for April 30, 2030) to develop PROTECT (Prediction of Relapse on OUD Treatment using Machine Learning-driven Evidence-based Clinical Decision Support Tool). The project addresses a critical public health need, as 5.5 million Americans have opioid...

Federal Project Grant Award Summary The National Institute on Drug Abuse awarded the University of Pittsburgh a $488,334 Project Grant effective September 30, 2025, through August 31, 2027, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct the PeRsOnlized MethadOne TrEatment (PROMOTE) study. This research initiative adapts and tests implementation facilitation strategies to support systematic shared decision-making (SDM) implementation within opioid treatment programs...

Federal Project Grant Award Summary The University of Florida's Division of Sponsored Research received a $439,826 project grant from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and evaluate BUP-CARE, a machine-learning-based clinical decision support tool designed to predict buprenorphine care discontinuity in opioid use disorder (OUD) treatment. The award, effective March 1, 2026 through February 28, 2028, addresses the...

Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded Massachusetts General Hospital $395,280 under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and evaluate AMP-C, a digital therapeutic (DTX) intervention targeting reward dysfunction in individuals with co-occurring Cannabis Use Disorder (CUD) and Major Depressive Disorder (MDD). This five-year project grant, effective July 1, 2025 through June 30, 2030, delivers a user-centered digital...

Federal Grant Award Summary Boston University Medical Campus received a $1.478 million Project Grant from the National Institute on Drug Abuse (Drug Use and Addiction Research Programs, CFDA 93.279) awarded September 30, 2025, through May 31, 2030. The BUP-BOOSTeR (Behavioral Optimization for Overcoming Suboptimal Treatment Retention) project will develop and optimize a multicomponent behavioral intervention to improve buprenorphine treatment retention in persons with opioid use disorder....

The National Science Foundation (NSF) Division of Information and Intelligent Systems awarded a $162,827 Project Grant to the University of Wisconsin - Madison, through the University of Wisconsin System, to develop an "Intelligent Pervasive Augmented Reality Therapy (IPAL)" system for managing opioid use disorder (OUD) and addiction. The 1-year project will integrate complementary psychotherapies like cognitive behavioral therapy and heart rate variability biofeedback with immersive...