Project Grant R01DA063631
- The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), awarded a $1,445,752 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to New York University School of Medicine. The grant, titled "Characterizing Complex OUD Care Trajectories and Outcomes Following Acute Service Utilization: A Population-Based Data Linkage Study," aims to apply novel research approaches to better understand real-world opioid use disorder (OUD)...
- This $265,302 Project Grant awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) supports research to investigate the neural mechanisms underlying opioid use disorder (OUD) and relapse risk during abstinence. The funded project will map the functional and anatomical pathways between the anterior and posterior paraventricular nucleus of the thalamus (PVT) and the nucleus accumbens (NAc), which have been implicated in the...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), is focused on evaluating the impact of state policies that facilitate the initiation of medication-based treatment for opioid use disorder (OUD) in emergency department settings. The $794,574 grant will fund a 5-year project to: 1) create a public database of state laws related to emergency department-based initiation of medications for OUD treatment; 2) analyze national...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will support a study to characterize treatment utilization and identify predictors of treatment engagement during the critical community re-entry period for adults with opioid use disorder (OUD) who have completed residential OUD treatment. The $147,486 award, with a performance period from December 20, 2024 to August 31, 2026, will leverage innovative...
- The National Science Foundation (NSF) awarded a $321,842 Project Grant under the Computer and Information Science and Engineering (CISE) program to Arizona State University, doing business as Orspa, to develop and test innovative technologies for aiding the sustainable recovery of opioid use disorder (OUD). The research focuses on three key areas: 1) effective physiological feature identification and extraction to detect craving that is generalizable across OUD patients, 2) machine learning...
- This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $405,625.00 to Florida International University to investigate the potential benefits of the autophagy activator TFEB in mitigating opioid use disorder (OUD) and overdose in mice. The research aims to evaluate how TFEB overexpression or knockdown impacts opioid-induced effects on mu-opioid receptor desensitization, internalization, and...
- This federal Project Grant award of $798,828.00 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to discover novel small molecule therapeutics for the safe and effective treatment of opioid use disorder (OUD). The key products and services to be delivered include: The development of an AI platform called M3.AI that will integrate target-based and phenotype-based methodologies to efficiently identify new drug candidates for OUD...
- This Project Grant award, valued at $190,625.00, was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The purpose of the award is to identify and characterize molecular markers of neuronal inhibition following exposure to opioids, with a focus on the nucleus accumbens region of the brain. Specifically, the research aims to: 1) Identify immediate early genes expressed in response to pharmacological inhibition of the...
- This $189,500.00 Project Grant award was provided by the National Institute on Drug Abuse (NIDA), which is part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The project aims to determine the extent to which cardiovascular disease (CVD) affects people with opioid use disorder (OUD) and identify ways to prevent CVD in this population. To achieve this, the project will: 1) Examine the relationship between CVD and OUD using Transformed...
- This federal Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 Drug Abuse and Addiction Research Programs) provides $1,093,394 to the University of Illinois to develop the "CHICAGO DATA-DRIVEN OUD SCREENING, ENGAGEMENT, TREATMENT AND PLANNING (C-DOSETAP) SYSTEM". The two-year project aims to leverage machine learning, prescription data, and patient-reported measures to assess and address opioid use disorder (OUD) risk and associated health disparities on...
The University of Florida received a $779,327 Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) on August 15, 2025. The grant, titled "Prediction of Relapse on OUD Treatment Using Machine Learning-Driven Evidence-Based Clinical Decision Support Tool (PROTECT)", aims to develop a machine learning-based clinical decision support tool to help primary care practitioners identify patients with opioid use disorder (OUD) who are at elevated risk of relapse while on buprenorphine treatment. The goal is to enable timely implementation of targeted relapse prevention interventions. This work is critical given the ongoing opioid crisis, with over 5.5 million Americans having OUD and over 81,000 opioid overdose deaths in 2023. The project is set to be completed by April 30, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $13.4k | 9/10/25 | ||
| Not listed | $766.0k | 8/4/25 |