Project Grant R41EY039129
- The National Eye Institute awarded Nanoscope Instruments, Inc., $1,019,678 on September 1, 2026, under the Vision Research program (CFDA 93.867) to develop and validate the Multi-Luminance Shape Discrimination Test, a device that measures functional vision in patients with moderate to severe vision loss. The recipient will evaluate the retest variability and performance of the Multi-Luminance Shape Discrimination Test in patients with geographic atrophy, wet age-related macular degeneration,...
- The National Eye Institute awarded Perzeption Inc. $305,406 on September 1, 2026, under the Vision Research program (CFDA 93.867) to develop and evaluate an efficient photostress recovery assessment method for age-related macular degeneration. The project addresses the need for sensitive functional biomarkers to detect early-stage AMD and measure disease progression or treatment response. Perzeption will develop a novel, personalized, adaptive testing method to assess photostress recovery in...
- The National Eye Institute awarded The New England College of Optometry $371,997 on June 1, 2026, under the Vision Research program (CFDA 93.867) to test a novel emmetropization mechanism model based on spectral and spatial opponent information in young children with myopia. The project will investigate how the retina controls eye growth and refraction through a blue-versus-yellow spectral-opponent mechanism. The research tests whether imbalances in retinal spectral and spatial...
- The National Eye Institute awarded N'waii Inc. $697,600 on September 30, 2025, under the Vision Research program (CFDA 93.867) to develop first-in-class mitochondrially targeted antioxidants for dry eye disease treatment. Work will be performed in Chicago, Illinois, with a completion date of September 29, 2027. The project focuses on a proprietary small-molecule lead candidate designed to address oxidative stress and mitochondrial dysfunction underlying meibomian gland dysfunction, a predominant...
- The National Eye Institute awarded Massachusetts Eye and Ear Infirmary $467,277 on July 1, 2026, under the Vision Research program (CFDA 93.867) to develop and validate a clinical neuropsychological assessment battery combined with mobile eye tracking to characterize the visuoperceptual profile of cerebral visual impairment. The testing battery comprises five standardized neuropsychological assessments focused on evaluating visual scanning, planning, processing speed, and visuomotor...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded a $421,136 Project Grant to the University of Maryland, College Park, effective August 1, 2025, through July 31, 2027, under the Vision Research program (CFDA 93.867). This award supports research into advanced wavefront shaping techniques designed to enable high-resolution fundus imaging in patients with ocular opacities—conditions affecting the cornea and lens that currently prevent effective posterior segment eye...
- The National Eye Institute awarded $753,787 to The General Hospital Corporation (doing business as Massachusetts General Hospital) on August 1, 2026, under the Vision Research program (CFDA 93.867) to develop low-cost ultra-widefield retinal optical coherence tomography (OCT) technology based on photonic-electronic integration. The project addresses cost barriers that limit clinical availability of OCT instrumentation used to detect and monitor diabetic retinopathy, age-related macular...
- The National Eye Institute awarded Neurofieldz Inc. $375,940 on September 15, 2025, under the Vision Research program (CFDA 93.867) to develop and validate a portable wireless diagnostic system for optic neuropathies and other diseases of the afferent visual system. Neurofieldz will conduct a Phase I Small Business Innovation Research feasibility study to advance NeuroVEP, a breakthrough sensor system that measures visual evoked potentials at the visual cortex using electric field...
- The National Eye Institute awarded the University of California Irvine $388,206 on September 1, 2026, under the Vision Research program (CFDA 93.867) to develop VisionKB, a single-cell multi-omics knowledgebase for the visual system. The award funds three specific deliverables: construction of a curated single-cell multi-omics reference atlas of the eye; development of a code-free, collaborative data-analysis platform; and delivery of an AI-powered co-pilot for automated data access and...
- The National Eye Institute awarded the University of California, Berkeley $143,031 on December 4, 2025, under the Vision Research program (CFDA 93.867) to computationally model the role of spatial phase in the selectivity and invariance of responses in primary visual cortex (V1) and secondary visual cortex (V2) to intermediate-level features in natural images. The modeling-driven research will investigate how phase-related computations operate across V1 and V2 and generate testable predictions...
The National Eye Institute awarded Aeon Imaging LLC $311,748 on August 15, 2026, under the Vision Research program (CFDA 93.867) to design, build, and demonstrate a more accurate visual acuity test device that corrects for optical artifacts common in aging eyes while remaining cost-competitive with electronic VA tests. Current visual acuity measurements in older patients are compromised by uncontrolled pupil size, retinal illuminance, wavefront aberrations, wide-field glare, and crowding effects—particularly in cataract patients—making it unclear whether reduced VA stems from retinal or optical causes. Aeon is developing a Potential Vision Tester that projects visual stimuli using Maxwellian view and a standardized three-millimeter pupil. Prototype data indicate PVT visual acuity measurements exceed wall chart and electronic display results when correcting sphere and cylinder, though correction of higher-order aberrations has not yet improved acuity or standard deviation. The project addresses two workflow bottlenecks: requiring subjective refraction before autorefraction and measuring VA prior to pupil dilation. The award runs through July 30, 2027, with place of performance in Bloomington, Indiana. The assistance type is Project Grant under the National Eye Institute's mission to drive innovative research to understand the eye and visual system, prevent and treat vision diseases, and improve quality of life through vision research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $311.7k | 8/18/26 |