Project Grant R41AG085838

Award Date 9/25/24
Completion Date 5/31/26
Dollars Obligated $100K
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Rockville, MD 20852, USA
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The National Institute on Aging (NIA) awarded a $1,193,500 Project Grant (CFDA 93.866 - Aging Research) to the Lovelace Biomedical Research Institute to investigate the mechanisms by which transcranial alternating current stimulation (tACS) and transcranial direct current stimulation (tDCS) modulate cerebral microcirculation and endothelial function. The research aims to dissect the effects of these transcranial electrical stimulation (TES) techniques on vascular responses and their potential...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $632,334 to the Massachusetts Eye and Ear Infirmary to investigate the contributions of vestibular, somatosensory, and visual dysfunction to imbalance and falls in older adults. The research aims to determine how sensory deficits and central processing changes impact standing balance, with a focus on vestibular function. The award will fund a large cohort study using quantitative...
The National Institute on Aging (NIA) awarded a $227,740 Project Grant (CFDA 93.866 - Aging Research) to the University of Florida to investigate the effects of transcutaneous spinal direct current stimulation (tsDCS) as an adjunct therapy to dynamic balance training in older adults with balance and walking deficits. The study aims to assess whether active tsDCS combined with balance training can enhance practice-related gains and retention in balance and walking performance, and whether this is...
This $804,795 Project Grant was awarded on September 18, 2024 by the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866). The funding supports a comprehensive research project investigating the neural mechanisms underlying the relationship between gait and cognitive function in individuals with subjective cognitive decline and a family history of Alzheimer's disease. The project aims to determine how declines in vestibular system function and...
This $295,000 Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) supports Neurogeneces, Inc., a small business, in developing a machine learning algorithm to assess "brain age" from at-home EEG sleep data. The goal is to provide an objective, interpretable measure of age-adjusted brain function that can facilitate early detection of cognitive decline. Through this Phase I Small Business Technology Transfer (STTR) project, Neurogeneces will...
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The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded Weinberg Medical Physics, Inc. a $100,000 Project Grant (R41AG085838) to conduct a comprehensive clinical study on using transcranial magnetic stimulation (TMS) guided by magnetic resonance imaging (MRI) and electroencephalography (EEG) to treat balance deficits in elderly patients with a history of falls. The project aims to build on early human study data showing that this TMS-based approach can improve short-term balance in elderly subjects by altering brain balance circuit activation patterns. If technically successful, the company intends to pursue further validation studies and commercialize the technology by integrating the MRI, EEG, and TMS functionalities into a single compact mobile device for use in geriatric, otolaryngology, and nursing home settings to address balance impairment and other neurological disorders in the elderly population.

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