Project Grant R37CA315609
- The National Cancer Institute awarded Rutgers The State University of New Jersey, doing business as RBHS-School of Nursing, $170,930 under Project Grant R03CA308463 on April 1, 2026, to support research into the longitudinal dynamics of blood microbiome and circulating tumor cells in metastatic breast cancer. The research applies a novel reduced metagenomic sequencing technique to analyze longitudinal plasma samples from women with metastatic triple-negative breast cancer (MTNBC), using liquid...
- The National Cancer Institute awarded Rutgers The State University of New Jersey, doing business as RBHS-School of Nursing, $599,978 under the Cancer Cause and Prevention Research program (CFDA 93.393) on July 1, 2026. The award funds a five-year prospective cohort study examining the relationship between perceived social obligations and clinical and patient-reported outcomes in 315 patients with advanced, poor-prognosis cancer. The research tests the hypothesis that higher patient-reported...
- The National Cancer Institute, a division of the Department of Health and Human Services, awarded $641,071 to Rutgers The State University of New Jersey (School of Nursing) on September 1, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct epidemiological research characterizing the role of air pollution in breast cancer prognosis and survivorship among Black women. The research leverages the Women's Circle of Health Follow-Up Study, a population-based cohort...
- Federal Grant Award Summary The National Cancer Institute awarded a $425,573 Project Grant to Magee-Womens Research Institute and Foundation under the Cancer Treatment Research program (CFDA 93.395) for the period of July 1, 2025 through June 30, 2027. The grant funds research to identify specific gut bacteria species, metabolites, and metabolic pathways associated with mammographic breast density (MBD) as a modifiable risk factor for breast cancer prevention. The research will employ...
- The National Cancer Institute awarded Rutgers, The State University of New Jersey, School of Nursing $239,352 on August 11, 2026, under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to develop a sequencing-free PCR-based method for deep T-cell receptor profiling using sloppy molecular beacons in single-cell droplet digital PCR. The recipient will deliver a diagnostic technique that identifies T-cell receptor variable gene segment usage while preserving alpha-beta chain...
- The National Cancer Institute awarded Rutgers The State University of New Jersey, doing business as RBHS-School of Nursing, $303,431 on August 13, 2026, under the Cancer Research Manpower program (CFDA 93.398) to implement breast cancer early detection measures in primary healthcare facilities in Botswana. The award funds a five-year implementation research project guided by the Integrative Systems Praxis for Implementation Research (INSPIRE) methodology. The project will conduct key informant...
- The National Cancer Institute awarded Hackensack University Medical Center $460,254 on July 16, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393, Assistance Listing Project Grant) to identify predictive and prognostic adipome biomarkers in obese triple-negative breast cancer mice for targeted therapy development. The funded research investigates how obesity-modified adipomes—large extracellular vesicles derived from adipose tissue—regulate triple-negative breast cancer...
- This Project Grant award, provided by the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395), will fund a pilot study to evaluate the associations of pre- and post-chemotherapy and -radiotherapy gut microbiome profiles with breast cancer recurrence and mortality. The $175,000 award will support the use of shotgun metagenome sequencing on 110 post-treatment stool samples from the Vietnam Breast Cancer Study, as well as an investigation of the impact of...
- The National Institutes of Health National Cancer Institute awarded $689,865 to The Trustees of Columbia University in the City of New York on August 5, 2026, under the Cancer Biology Research program (CFDA 93.396) to develop methodological tools and frameworks for cancer microbiome study design and analysis. The award funds development of a comprehensive toolset to address contamination and batch-effect challenges in tumor microbiome research. Specific deliverables include a new method to...
- The National Cancer Institute awarded Rutgers The State University of New Jersey, doing business as RBHS-School of Nursing, $516,808 under the Cancer Treatment Research program (CFDA 93.395) on June 1, 2026, to elucidate the mechanism of targeting methionine synthase (MTR) to enhance anti-tumor immunity in KRAS-driven lung cancer. The recipient will conduct research to understand how MTR targeting enhances immune responses in KRAS-driven non-small cell lung cancer (NSCLC), which exhibits...
The National Cancer Institute awarded Rutgers The State University of New Jersey, School of Nursing, $723,569 under the Cancer Cause and Prevention Research program (CFDA 93.393) on September 1, 2026, to conduct a prospective epidemiologic study examining associations between the human gut microbiome and postmenopausal breast cancer risk. The research leverages the Nurses' Health Study II cohort, which includes over 18,000 women with pre-diagnostic stool samples and repeated assessments of diet and lifestyle. The study integrates stool metagenomics and metabolomics with circulating sex hormone and inflammation biomarkers to evaluate whether specific gut microbial features—including taxonomic composition, functional pathways, and stool microbial metabolites—contribute to breast cancer risk through hormone-related and non-hormonal mechanisms. The first aim identifies associations of pre-diagnostic microbial features in relation to subsequent breast cancer risk in a nested case-control study with 500 incident breast cancer cases and 500 matched controls, stratified by estrogen receptor status. The project addresses a critical gap in existing literature by providing the first large-scale prospective study applying whole-metagenome sequencing to characterize the stool microbiome and metabolome before breast cancer diagnosis, establishing whether microbiome alterations are causal or consequential to disease. Work is performed in Newark, New Jersey. The project period runs through August 31, 2031. The award is classified as a Project Grant, an assistance type supporting investigator-initiated research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $723.6k | 8/21/26 |