Federal Grant Award Summary Beth Israel Deaconess Medical Center, Inc. received a $3.27 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded June 15, 2025, with an ultimate completion date of March 31, 2030. The award supports research to identify proteomic signatures associated with postoperative delirium and long-term cognitive decline in older cardiac surgical patients. Building on the successful DEXACET trial demonstrating...
Federal Grant Award Summary The National Institute on Aging (part of the National Institutes of Health) awarded Vanderbilt University Medical Center a $3.15 million Project Grant on September 1, 2025, under the Aging Research program (CFDA 93.866) to investigate the relationship between serum psychotropic drug levels, drug metabolizer status, and delirium duration in hospitalized older adults. The research project, which extends through June 30, 2030, addresses a critical clinical challenge:...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $161,500.00 to investigate the role of perineuronal nets (PNN) in the development of postoperative delirium in aged mice. The research aims to test the hypothesis that changes in PNN and parvalbumin-positive neurons coincide with delirium-like cognitive impairment in aged mice subjected to anesthesia, surgery, and intensive care unit (ICU)-like conditions. The project will also examine whether...
The National Institute on Aging awarded $758,049 to the University of Wisconsin-Madison on September 15, 2025, under the Aging Research program (CFDA 93.866) to establish the Lucidity in Alzheimer's and Dementia (LEAD) Network. This project grant, with completion targeted for August 31, 2027, will create an integrated research infrastructure to advance measurement science and interdisciplinary collaboration focused on lucid episodes (LE)—transient recoveries of cognitive function observed in...
Federal Project Grant Award Summary Vigorous Mind, Inc. received a $499,981 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) awarded on August 1, 2025, with a completion date of July 31, 2026. The grant funds the development and feasibility demonstration of an autonomous robot designed to deliver a multicomponent non-pharmacological intervention to reduce delirium in hospitalized elderly patients living with dementia. Delirium, an acute...
This $2,365,042 Project Grant was awarded by the National Institute on Aging (NIA) under the Aging Research Federal Grant Program (CFDA 93.866) to conduct research on the biological underpinnings of Alzheimer's disease and related dementias (ADRD). The research aims to better characterize the interplay between biological markers of neurodegeneration, vascular, nutritional, and inflammatory systems, and their interface with social and economic factors, by leveraging cross-national comparisons...
The University of California, Los Angeles received a $2.7 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded September 1, 2025, with completion scheduled for August 31, 2029. This research project will generate rigorous evidence comparing health outcomes for older patients with Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD) who are discharged from hospitals to home-based care versus facility-based...
Federal Grant Award Summary The National Institute on Aging (NIA) awarded $3.26 million to The Feinstein Institutes for Medical Research under its Aging Research program (CFDA 93.866) on June 15, 2025, for a prospective observational cohort study examining oropharyngeal dysphagia (OD) improvement in hospitalized patients with Alzheimer's disease and related dementias (AD/ADRD). The project, which extends through February 28, 2030, will develop a machine learning model to predict which AD/ADRD...
This $1,933,556 Project Grant awarded by the National Institute on Aging (NIA) under its Aging Research program (CFDA 93.866) will support research to assess the impact of hospital-based health information technology (hospital-HIT) on healthcare quality and equity for patients with Alzheimer's disease and related dementias (ADRD). The primary awardee, the University of Maryland, College Park, will conduct a ten-year longitudinal study to evaluate how hospital-HIT systems that promote care...
This Project Grant award of $4,787,820.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to gain a better understanding of the individual- and system-level characteristics that influence diagnosis of mild cognitive impairment (MCI) and Alzheimer's disease and related dementias (ADRD), and how diagnosis can moderate the effects of cognitive decline on employment, future care, and quality of life. The key objectives are to: 1) examine whether older adults experiencing...
This $162,745 Project Grant from the National Institutes of Health's National Institute on Aging will support research to improve identification of delirium. Specifically, the grantee will determine the four most commonly used and well-validated delirium identification instruments. They will then harmonize these instruments to generate an item bank and identify optimal cut-points to determine whether a patient has delirium. This work aims to create a unified approach to delirium identification that will advance both clinical care and research. The harmonized item bank is intended to facilitate combining studies and meta-analyses, which are essential for clinical guideline development. Completion of this project should help lay the foundation for the principal investigator's future career in aging research as a physician scientist.