Project Grant R35NS132231

Award Date 9/1/24
Completion Date 8/31/32
Dollars Obligated $885K
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
Durham, NC 27710, USA
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The federal Project Grant award R35NS132231, totaling $885,128.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. This grant supports research conducted by Duke University to develop a molecular-level understanding of the design principles governing somatosensation and nociception by membrane sensory receptor channels. The research aims to study the structure, function, and pharmacology of these sensory receptors, particularly their role in the detection and transmission of sensory stimuli such as temperature changes and irritants. Additionally, the project seeks to investigate disease mutations in these receptors and explore the development of non-opioid drugs to treat conditions ranging from chronic itch to migraine. This 8-year project, beginning on Sep 1, 2024, will be carried out by Duke University's research team at their facilities in Durham, North Carolina.

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