Project Grant R35GM164167
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stanford University a $410,256 Project Grant on September 15, 2025, under the Biomedical Research and Research Training program (CFDA 93.859) to develop generative multiscale models of biomolecular conformational dynamics. The primary deliverable is an integrated research program combining physics-based computational modeling with artificial intelligence techniques to advance conformational sampling...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stanford University a $157,388 Project Grant on August 9, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support fundamental research on nucleosome engagement through chemically induced proximity (CIP) methodology. The research initiative, scheduled for completion by August 8, 2027, aims to develop novel approaches for rewiring protein-nucleosome interactions by...
- Federal Grant Award Summary Stanford University received a $616,000 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded March 12, 2026, with completion targeted for February 29, 2028. The grant funds research to develop next-generation proximity labeling (PL) enzymes—specifically FLEXID and LACCID—designed to enhance mapping of spatial proteomes and molecular interactions within living...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Leland Stanford Junior University a $423,500 Project Grant (CFDA 93.859: Biomedical Research and Research Training) effective April 1, 2026, with a completion date of January 31, 2031. The research project focuses on understanding the regulatory mechanisms that control mitochondrial transport and quality control in neurons. The research team will investigate how cellular signals converge to...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Leland Stanford Junior University a $385,000 Project Grant on March 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support fundamental research on three-dimensional (3D) genome folding in single cells. The research project, scheduled for completion by December 31, 2030, will develop and implement systematic large-scale genetic and chemical perturbation...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Leland Stanford Junior University a $125,000 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) effective May 1, 2026, through April 30, 2028. This award supports the development of innovative membrane-centric proximity labeling technologies to systematically map lipid-protein and protein-protein networks in living cells. The research deliverables include the...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stanford University a Project Grant of $488,783 under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025, through July 31, 2030. This five-year Maximizing Investigators' Research Award (MIRA) funds fundamental research to decode the cell surface chemistry and function of Staphylococcus aureus, a gram-positive bacterium that poses significant challenges...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Leland Stanford Junior University a Project Grant of $494,796 under the Biomedical Research and Research Training program (CFDA 93.859), effective March 1, 2026, through December 31, 2030. This award supports fundamental research on myosin structure and function, specifically investigating how mutations in cardiac myosin and myosin-binding protein C cause familial hypertrophic...
- Federal Grant Award Summary Stanford University received a $462,119 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded September 8, 2025, with completion targeted for July 31, 2029. The grant supports the development and application of TRACK-IT (Transposon Accelerated Chromatin Kinetic Imaging Technology), a novel live-imaging platform designed to visualize and characterize...
- Federal Project Grant Award Summary The Leland Stanford Junior University received a $423,500 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 6, 2026, with completion targeted for February 28, 2031. This award funds fundamental research to elucidate the molecular mechanisms governing membrane protein complex assembly at the human endoplasmic reticulum (ER) membrane....
The National Institute of General Medical Sciences (NIGMS) awarded Stanford University a $285,031 Project Grant (CFDA 93.859: Biomedical Research and Research Training) effective June 1, 2026, through May 31, 2031, to investigate the role of ubiquitin-fold modifier 1 (UFM1) conjugation in ribosome quality control (RQC). The research program will elucidate the molecular mechanisms by which UFM1ylation coordinates the disassembly and clearance of stalled ribosomes at the endoplasmic reticulum, a process essential for maintaining translational fidelity and cellular proteostasis. This fundamental research will define how UFM1ylation regulates ribosome recycling under both normal termination and stress-induced conditions. The project will employ a multidisciplinary research approach integrating genetics, biochemical reconstitution, cryo-electron microscopy, and ribosome profiling to delineate UFM1ylation's interface with canonical RQC pathways and its cellular stress adaptation mechanisms. Conducted at Stanford University's Palo Alto, California facility under the R35 (Maximizing Investigators' Research Award) mechanism, the research aims to establish foundational discoveries that may be expanded to explore how dysregulation of this pathway affects cell viability and stress resilience, with potential implications for understanding cellular responses to proteostatic challenges.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $285.0k | 5/22/26 |