Project Grant K99GM163005
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stanford University a $616,000 Project Grant on March 12, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop next-generation proximity labeling (PL) enzymes for enhanced spatial proteome mapping in living cells. The research initiative, to be completed by February 29, 2028, will focus on optimizing two innovative enzymes—FLEXID and LACCID—to overcome...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Leland Stanford Junior University a $385,000 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) effective September 1, 2025, with completion targeted for June 30, 2030. This award supports fundamental research investigating de novo evolved lipid transport and processing mechanisms in Plasmodium parasites that interface with human cells. The research aims...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Leland Stanford Junior University a Project Grant of $192,500 under the Biomedical Research and Research Training program (CFDA 93.859) for the period September 1, 2025 through August 31, 2027. The award funds the development of SPLASH (Split Protein Ligation Activated by Steroid Hormone), a novel drug-regulated protein induction system designed to enable rapid, controllable production of...
- Federal Grant Award Summary The National Institute of General Medical Sciences awarded Stanford University a $382,712 Project Grant on May 15, 2025, under the Biomedical Research and Research Training program (CFDA 93.859) to develop and apply advanced microfluidic technologies for large-scale enzyme characterization. The project leverages the High-Throughput Microfluidic Enzyme Kinetics (HT-MEK) platform to enable parallel expression, purification, and quantitative assay of over 1,000...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded a Project Grant of $2,117,247 to The Leland Stanford Junior University, effective September 11, 2025, through August 31, 2029, under the Biomedical Research and Research Training program (CFDA 93.859). This award supports fundamental research into the genetic basis of complex traits, spanning evolutionary organisms from archaea and yeast to humans. The funded research will develop and apply...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Leland Stanford Junior University a Project Grant totaling $225,144 (awarded August 9, 2026; completion date February 15, 2029) under the Biomedical Research and Research Training program (CFDA 93.859) to develop self-assembling pyrrole-imidazole polyamides (PY-IM PA) for treating Friedreich's ataxia and prostate cancer. The research addresses a critical gap in pharmaceutical development by...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Leland Stanford Junior University a Project Grant of $385,000 under the Biomedical Research and Research Training program (CFDA 93.859) to support fundamental research investigating the rules governing three-dimensional (3D) genome folding in single cells. The award, initiated March 1, 2026, and extending through December 31, 2030, funds the principal investigator's research program to...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stanford University a Project Grant totaling $590,806 on September 12, 2025, under the Biomedical Research and Research Training program (CFDA 93.859). Under Principal Investigator Ron Dror's direction, the award funds research advancing structure-based drug discovery through machine learning and molecular simulation over a five-year performance period concluding August 31, 2030. The project...
- Federal Project Grant Award Summary Stanford University received a $423,500 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded on March 6, 2026, with completion scheduled for February 28, 2031. The award supports fundamental research aimed at dissecting the molecular mechanisms that regulate membrane protein complex assembly at the human endoplasmic reticulum membrane. The project...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stanford University $157,388 under the Biomedical Research and Research Training program (CFDA 93.859) to support a one-year research project titled "Rewiring Nucleosome Engagement Through Chemically Induced Proximity." The award, granted on August 9, 2026, with a completion date of August 8, 2027, funds investigator-initiated basic biomedical research conducted at Stanford's Palo...
The National Institute of General Medical Sciences (NIGMS) awarded The Leland Stanford Junior University a $125,000 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) effective May 1, 2026, through April 30, 2028. This award supports the development of innovative membrane-centric proximity labeling technologies designed to map lipid-protein and protein-protein interaction networks in living cells. The research will produce conditionally activated proximity labeling enzymes that respond to their membrane microenvironment, with two primary deliverables: Antigen-Controlled Turboid (ACTURBO), an enzyme activated upon binding to proteins of interest for studying compartment-specific opioid receptor signaling in neurons, and Lipid-Activated Biotin Ligases (LABL) for phosphoinositide-centric mapping of oncogenic lipid signaling pathways. These research products will establish a versatile framework for investigating membrane dynamics and their regulation of cellular signaling in both normal and degenerative biological conditions. The research will be conducted at Stanford's Palo Alto, California facility and represents NIGMS's commitment to funding fundamental basic research that advances understanding of biological processes and establishes foundations for disease diagnosis and treatment innovations.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $125.0k | 4/7/26 |