Project Grant R35GM163933
Award Date 9/1/26
Completion Date 4/30/31
Dollars Obligated $566K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Austin, TX 78712, USA
Similar Awards
- The National Institute of General Medical Sciences awarded the University of Texas at Austin $386,811 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop synthetic platforms for studying multivalent molecular recognition and communication. The funded research, led by the Callmann Lab, will create programmable polymeric scaffolds that isolate and systematically test individual variables—density, stereochemistry, topology, and...
- The National Institute of General Medical Sciences awarded the University of Texas at Austin $771,265 on September 15, 2025, under the Biomedical Research and Research Training program (CFDA 93.859) to conduct structural and functional imaging of macromolecular machines involved in gene regulation using cryo-electron microscopy. The research encompasses three principal investigative avenues: mechanisms of RNA-guided CRISPR-Cas surveillance, methods to determine structures of human protein...
- The National Institute of General Medical Sciences awarded the University of Texas at Austin $310,750 on May 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop chemical language models for peptide engineering and discovery. The project develops deep-learning language models designed to support therapeutic peptide discovery, optimization, and application. Existing protein and small-molecule language models lack reliable formats for peptide analysis and...
- The National Institute of General Medical Sciences awarded The University of Texas Southwestern Medical Center $433,780 on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop innovative chemical reactions for drug discovery. The funded research pursues two research directions. First, the recipient will develop stereoselective catalytic reactions to synthesize chiral N-heterocycles—sp3-rich scaffolds prevalent in FDA-approved drugs—using...
- The National Institute of General Medical Sciences, part of the National Institutes of Health within the Department of Health and Human Services, awarded The University of Texas Southwestern Medical Center $488,525 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859), a Project Grant (R35GM162011). The award funds evolution-guided studies of mitochondrial activities and the host response to infectious agents. The research characterizes newly identified...
- The National Institute of General Medical Sciences awarded the University of Texas at Austin $429,650 on April 6, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the interplay between cellular metabolism, chromatin regulation, and transcriptional control in ethylene signaling and stress responses in Arabidopsis. The research explores how chromatin-modifying enzymes utilize metabolic cofactors to influence histone modifications, nucleosome structure,...
- Federal Grant Award Summary The University of Texas Southwestern Medical Center received a $2.23 million Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 3, 2025, through August 31, 2029. The grant funds a five-year research program focused on elucidating the catalytic mechanisms and regulatory roles of bacterial alarmone hydrolases—enzymes that degrade (p)ppGpp, a...
- The National Institute of General Medical Sciences, part of the Department of Health and Human Services National Institutes of Health, awarded The University of Texas Southwestern Medical Center $449,900 on May 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop new methods for detecting protein phosphorylation in cells. The project will exploit a novel bacterial effector protein, Legionella pneumophila LnaB, which attaches adenosine monophosphate...
- Federal Project Grant Award Summary The University of Texas Southwestern Medical Center received a $1.79 million Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 10, 2025, through August 31, 2029. The primary deliverable is the development and validation of a nuclear alpha-ketoglutarate (AKG) biosensor system—designated the AKG-ON biosensor—designed to measure and...
- The National Institute of General Medical Sciences awarded The University of Texas Southwestern Medical Center $456,500 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to explore RNA polymerase dynamics and regulatory architecture across divergent bacterial species. The recipient will develop and apply a new sequencing platform that enables purified RNA polymerase to transcribe entire bacterial genomes under defined biochemical conditions, with...