Project Grant R35GM163721
- Federal Project Grant Award Summary Rutgers The State University of New Jersey's School of Nursing received a $392,500 Project Grant awarded April 1, 2026, from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant funds a five-year research initiative (concluding March 31, 2031) focused on identifying approaches to modulate the activity of potassium (K+) ion channels, with particular emphasis on three...
- Federal Grant Award Summary Rutgers, The State University has received a $805,374 CAREER (Careers in Research, Teaching, and Personal Services) award from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective July 1, 2025 through June 30, 2030. This project grant supports fundamental research investigating mechanical signaling at the cell membrane, specifically examining how cells sense and respond to...
- Federal Grant Award Summary Rutgers, The State University received a $487,500 Project Grant award dated May 11, 2026, from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant supports fundamental research investigating the mechanisms of adaptive immunity in RNA-targeting CRISPR-Cas13 systems through the project completion date of January 31, 2031. The research will employ microbiological, genetic,...
- Federal Grant Award Summary Rutgers, The State University received a $573,035 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded February 15, 2026, with a completion date of January 31, 2031. The award supports research investigating the cellular mechanisms by which the mechanosensitive ion channel PIEZO1 controls cerebrospinal fluid (CSF) hydrodynamics and brain-waste clearance. The research addresses how disrupted CSF flow...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Rutgers The State University of New Jersey a $321,304 project grant under the Biomedical Research and Research Training program (CFDA 93.859) effective April 1, 2026, through March 31, 2031. This award supports fundamental research focused on understanding the metabolic regulation of innate immunity-dependent wound healing in vivo. The project employs zebrafish (Danio rerio) as an in vivo model...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded a $446,875 Project Grant to the University of Pennsylvania on March 6, 2026, under the Biomedical Research and Research Training program (CFDA 93.859). The research initiative, titled "Molecular Determinants of Voltage-Gated Ion Channels' Localization and Function," will be conducted through February 28, 2031, at the university's Philadelphia campus. This fundamental research...
- Federal Project Grant Award Summary The University of Florida received a $410,601 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 4, 2025, with a completion date of June 30, 2030. This five-year research initiative will advance understanding of the TRPM3 ion channel, a membrane protein critical to pain sensation and inflammatory response in nociceptor neurons. The...
- Federal Grant Award Summary Rutgers The State University of New Jersey received a $249,000 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through July 31, 2028. The research focuses on characterizing protein condensates and nuclear organization mechanisms that maintain genomic integrity, with particular emphasis on understanding how two critical tumor...
- Federal Project Grant Award Summary The University of Florida received a $320,750 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective April 1, 2026, through March 31, 2031. This R35 Maximizing Investigators' Research Award supports fundamental research investigating the genetic and molecular mechanisms connecting mechanotransduction to lipid metabolism. The research will employ...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Rutgers, The State University of New Jersey, Camden Division a Project Grant of $423,734 under the Biomedical Research and Research Training program (CFDA 93.859) to develop in vivo genetic and molecular platforms for investigating the co-evolution of cell-signaling proteins. The award, effective February 12, 2026, and concluding December 31, 2030, supports research utilizing Drosophila melanogaster...
Rutgers The State University of New Jersey received a $533,456 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2026, through June 30, 2031. This R35 award supports investigator-initiated basic research focused on elucidating the molecular regulation of mechanically-activated PIEZO2 ion channels and calcium-selective TRPV6/5 ion channels. The research will deliver mechanistic insights into how specific plasma-membrane phospholipids regulate these critical ion channels involved in somatosensory touch, tactile pain, and calcium homeostasis. The grant funds the development of an integrated lipid-centric framework for channel regulation and therapeutic targeting. Key deliverables include identification of the molecular basis for phospholipid inhibition of PIEZO2, characterization of intracellular signaling pathways that alter channel activity in sensory neurons and mechanosensation in mice, structure-guided screening and characterization of selective TRPV6/5 modulators, and analysis of disease-linked channel mutations. Upon completion, this research is intended to provide the scientific foundation for developing selective PIEZO2 inhibitors and TRPV6/5 potentiators with potential therapeutic applications, advancing both fundamental understanding of ion channel physiology and future drug development.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $533.5k | 6/12/26 |