Project Grant R35GM163637
Award Date 9/1/26
Completion Date 7/31/31
Dollars Obligated $420K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Bronx, NY 10461, USA
Similar Awards
- The National Institute of General Medical Sciences awarded $1.386 million to the University of Arizona on June 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to identify and modulate mechanistic cellular pathways of quiescence deepening and transition to senescence. The research focuses on elucidating the transcriptomic and epigenetic mechanisms controlling quiescence depth—a cellular dormancy state—and its progression into senescence by modulating the...
- The National Institute of General Medical Sciences, part of the Department of Health and Human Services National Institutes of Health, awarded New York University $421,737 on March 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop data-driven, predictive biophysical models of molecular mechanisms underlying cellular quiescence in microorganisms. The research focuses on quantitative relations between physiological traits and molecular processes in...
- The National Cancer Institute awarded Albert Einstein College of Medicine $2.038 million on August 26, 2026, under the Cancer Biology Research program (CFDA 93.396) to investigate mechanisms of early breast cancer local and distant relapse. The award supports a Project Grant (P01CA295557) with a period of performance through July 31, 2031, and place of performance in Bronx, New York. The research examines how disseminated cancer cells remain dormant in new tissue microenvironments and...
- The National Cancer Institute awarded Albert Einstein College of Medicine $168,000 on April 1, 2026, under the Cancer Treatment Research program (CFDA 93.395) to investigate dormancy and recurrence mechanisms in pancreatic ductal adenocarcinoma. The research examines how disseminated tumor cells in pancreatic cancer patients enter a dormant state, allowing minimal residual disease to persist after surgery and chemotherapy despite high initial response rates. The project focuses on two...
- The National Institute of General Medical Sciences, a component of the National Institutes of Health within the Department of Health and Human Services, awarded $1.764 million to Albert Einstein College of Medicine on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support research on the molecular mechanisms governing the elongation-to-termination transition of RNA polymerase II-dependent transcription. The funded research investigates how RNA...
- The National Cancer Institute awarded Icahn School of Medicine at Mount Sinai $712,912 for research into the functional determinants of disseminated tumor cell dormancy in the brain under the Cancer Biology Research program (CFDA 93.396), effective August 1, 2026. The recipient will conduct a five-year project through July 31, 2031 to explore how breast cancer cells reshape the brain microenvironment to establish and maintain a dormancy-supportive niche. The research centers on the role of...
- The National Institute of General Medical Sciences awarded Albert Einstein College of Medicine $361,200 on August 15, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop computational methods for predicting and simulating interactions between cell surface proteins with multiple domains in the immunoglobulin fold. The project addresses a fundamental challenge in structural biology: current experimental methods cannot reliably measure transient interactions...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded the University of California, Santa Barbara $430,375 on August 1, 2026, under the Research Infrastructure Programs (CFDA 93.351) to fund basic research on reversible stem cell dormancy in the basal chordate Botrylloides diegensis. The award supports investigation of mechanisms controlling stem cell dormancy and re-activation, using B. diegensis as a model organism. This species undergoes...
- The National Institutes of Health National Cancer Institute awarded Icahn School of Medicine at Mount Sinai $827,111 on July 21, 2026, under the Cancer Biology Research program (CFDA 93.396) to investigate the role of the proline hydroxylase P4HA2 in metastatic tumor dormancy and the dormancy-to-reactivation transition. The project examines how dormant disseminated tumor cells regulate collagen extracellular matrix formation through control of proline hydroxylation, hypothesizing that P4HA2...
- The National Institute on Aging awarded Albert Einstein College of Medicine $462,000 on September 1, 2026, under the Aging Research program (CFDA 93.866) to investigate chaperone-mediated autophagy in aging-associated cardiovascular fibrosis. The research examines the role of declining chaperone-mediated autophagy (CMA) activity in fibroblasts as a driver of progressive fibrotic remodeling in aging hearts and vessels. The study will test whether age-related CMA decline in cardiac fibroblasts...