Project Grant R01GM166716
- Federal Project Grant Award Summary Albert Einstein College of Medicine received a $462,000 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2030. The award supports fundamental research establishing a novel therapeutic approach to inhibit protein-protein interactions through ligand-transferred oxidation. The research program focuses on...
- Federal Grant Award Summary Albert Einstein College of Medicine received a $370,979 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2026, with completion expected July 31, 2031. The award funds fundamental research investigating the molecular mechanisms of dynein and KIF1A, two essential motor proteins responsible for long-distance intracellular transport. The research...
- Federal Grant Award Summary Albert Einstein College of Medicine received a $102,041 Project Grant award dated September 8, 2025, from the National Center for Advancing Translational Sciences (NCATS), under the CFDA 93.350 program, to establish the Building Bridges in the Bronx: Montefiore-Einstein Explore Translational Science Program (BRONX-MEETS). The program will develop and deliver a 10-week summer research education initiative designed to expose undergraduate and graduate students to...
- Federal Grant Award Summary Albert Einstein College of Medicine received a $3.2 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded June 18, 2026, with completion targeted for May 31, 2030. The award supports biomedical research investigating the interaction between TAR (trans-activation response) RNA and INI1/SMARCB1, a component of chromatin remodeling complexes critical...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Regents of the University of Colorado a Project Grant totaling $307,854 under the Biomedical Research and Research Training program (CFDA 93.859) to support basic research on RNA Polymerase II (Pol II) transcriptional termination mechanisms. The award, effective April 3, 2026, and completing December 31, 2029, funds investigator-initiated research to understand how messenger RNA (mRNA)...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded the University of California, Merced a Project Grant of $400,910 under the Biomedical Research and Research Training program (CFDA 93.859), effective June 1, 2026, with an ultimate completion date of March 31, 2031. This award supports computational research focused on understanding RNA Polymerase II (Pol II) elongation complex dynamics through molecular dynamics (MD) simulations. The project...
- Federal Grant Award Summary Albert Einstein College of Medicine received a $561,407 Project Grant award from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396) on June 18, 2026, with completion targeted for May 31, 2031. This award supports fundamental research investigating the causal mechanisms driving germline predisposition to myeloproliferative neoplasms (MPNs). The project utilizes genome-wide association study (GWAS) findings to elucidate how...
- Federal Project Grant Award Summary Harvard Medical School, operating under the President and Fellows of Harvard College, received a $165,279 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2026, with an ultimate completion date of May 31, 2031. The award supports fundamental research dissecting the control of transcription elongation by RNA Polymerase II (RNAPII),...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded a $420,476 Project Grant to the University of Texas Health Science Center at Houston under the Biomedical Research and Research Training program (CFDA 93.859) for the period August 1, 2026, through July 31, 2031. The award funds structural and mechanistic studies of eukaryotic gene transcription regulation, specifically investigating how the CDK8 kinase module (CKM)—comprising MED13, MED12, CDK8, and...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded $299,673 to The Research Foundation For The State University Of New York under the Biomedical Research and Research Training program (CFDA 93.859) on April 1, 2026, for research investigating the regulatory mechanisms of in vivo transcriptional dynamics. The research will be conducted at the University at Albany through December 31, 2030. The project aims to elucidate how transcriptional...
Albert Einstein College of Medicine received a $1.764 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded August 1, 2026, with completion targeted for July 31, 2030. The grant supports investigator-initiated basic research focused on unraveling the molecular mechanisms governing the elongation-to-termination transition of RNA Polymerase II (Pol II)-dependent transcription. The research addresses a critical gap in understanding how transcriptional regulation transitions between elongation and termination phases, processes regulated by cyclin-dependent protein kinases (CDKs) and phosphatases. This fundamental research is designed to advance understanding of transcriptional regulation mechanisms that, when dysregulated, contribute to diseases including diabetes, neurological disorders, and cancer. The project delivers foundational scientific knowledge concerning the structural rearrangements and compositional changes that occur in the Pol II elongation complex during the transition to termination, including the handoff from elongation factors to mRNA 3'-end processing and termination factors. By identifying novel therapeutic targets and enhancing understanding of transcriptional misregulation, this research supports NIGMS's mission to generate basic biological knowledge that lays the foundation for advances in disease diagnosis, treatment, and prevention. The work is conducted at Albert Einstein College of Medicine's facility in Bronx, New York, positioning the institution as a research node within the NIH-funded biomedical research enterprise.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.8m | 7/9/26 |