Project Grant R35GM162083
- Federal Project Grant Award Summary The University of New Mexico, Office of Sponsored Projects Division, received a $1.83 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2029. The award funds a four-year research initiative titled "Redefining Nanomedicine Beyond One-Size-Fits-All: Uncovering Mechanisms of Sex Differences and...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Massachusetts General Hospital a Project Grant of $439,088 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective July 8, 2025, through July 7, 2027. The award supports research led by Dr. Daniel Lingwood, Associate Professor of Medicine at the Ragon Institute of Mass General, MIT and Harvard, to mechanistically define how sex differences in hormones and...
- Federal Project Grant Award Summary The University of Miami, through its Office of Research Administration within the School of Medicine, received a $3.2 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) to conduct integrative analyses examining the X chromosome's contribution to Alzheimer's disease (AD). The five-year award, effective March 1, 2026, through February 28, 2031, will deliver comprehensive research services focused on...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $414,953 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award, effective August 1, 2025, through April 30, 2030, funds research investigating inflammasome-driven sexual dimorphism in glioma therapeutic responses. The research will examine how...
- Federal Grant Award Summary The University of Massachusetts Lowell received a $433,125 Project Grant award effective August 1, 2025, through the National Institute of General Medical Sciences' Biomedical Research and Research Training program (CFDA 93.859) to support fundamental research investigating the role of sex hormones in host-microbiome interactions within the human oral mucosa. The award, with completion scheduled for April 30, 2030, will fund the development and application of benchtop...
- Federal Project Grant Award Summary The University of Massachusetts Boston received a $422,173 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2025 through June 30, 2030. The award funds fundamental basic research investigating cellular signaling networks that control organism development and tissue patterning. The research employs the fruit fly Drosophila as a model...
- Federal Project Grant Award Summary The University of Florida's Division of Sponsored Research received a $2.33 million award from the National Institute on Aging under the Aging Research program (CFDA 93.866), effective September 1, 2025, through August 31, 2029. This project grant funds scientific research evaluating neuroimmune mechanisms and therapeutic targeting potential of the luteinizing hormone/chorionic gonadotropin (LH/CG) receptor in menopausal and Alzheimer's disease (AD) affected...
- Federal Project Grant Award Summary The University of Miami, through its Office of Research Administration within the School of Medicine Division, received a $663,854 Project Grant awarded August 1, 2025, by the National Institute of Biomedical Imaging and Bioengineering under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The research project, "Quantitative Dynamic Monitoring of Mesenchymal Stem Cells and MSC-Derived...
- Federal Project Grant Award Summary The University of Massachusetts Medical School received a $460,625 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded August 10, 2025, with completion targeted for July 31, 2030. This research project, titled "Decoding Cis-Regulatory Element Activity Through Deep Learning Frameworks," will deliver computational and experimental research...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded the University of Florida a Project Grant totaling $466,125 under the Biomedical Research and Research Training program (CFDA 93.859) to support fundamental research on RNA localization and local translation mechanisms. The five-year project, initiated August 1, 2025 and concluding May 31, 2030, will be conducted at the University of Florida's Jupiter, Florida facility. The research leverages...
The University of Miami's Office of Research Administration—School of Medicine Division received a $383,750 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded March 1, 2026, with completion scheduled for February 28, 2031. This award supports fundamental biomedical research investigating sex differences in the regulation of innate immune response by neurotransmitters, specifically examining how gamma-aminobutyric acid (GABA) and glutamate modulate monocyte and neutrophil activity in a sex-dependent manner. The research deliverables include systematic investigation of the epigenetic, transcriptional, and metabolic mechanisms underlying sex-specific immune cell programming and neurotransmitter response. The project will utilize mouse models, functional assays, and high-dimensional analytical approaches to determine the relative contributions of sex hormones versus chromosomes in establishing myeloid cell programs and to identify the specific molecular pathways that mediate sex-dependent GABA and glutamate effects on innate immune function. The research aims to advance fundamental understanding of myeloid cell biology and inform development of sex-specific therapeutic approaches, addressing a significant knowledge gap regarding how neurotransmitters modulate immune cell activity across biological sexes.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $383.8k | 2/27/26 |