The National Institute of General Medical Sciences (NIGMS) awarded a $401,233 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) federal grant program to Duke University, effective August 1, 2025 through May 31, 2030. The grant supports the development of new catalytic selective amination methods and aminofunctionalization cascades to expedite the synthesis and study of structurally diverse, nitrogen-containing molecules as probes and leads for advancing the understanding and treatment of human disease. The research aims to establish a chemical platform that can streamline the creation of novel nitrogen-containing molecules from readily available starting materials like alkenes, dienes, cyclopropanes, and functional molecules. Successful implementation of these studies is expected to greatly facilitate the synthesis and investigation of a wide range of nitrogen-containing molecules that are difficult or impossible to access with current technologies, benefiting organic synthesis, medicinal chemistry, biomedical research, and drug discovery.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $401.2k | 7/22/25 |