Project Grant R35GM158223
Award Date 9/5/25
Completion Date 8/31/30
Dollars Obligated $359K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Lexington, KY 40546, USA
Similar Awards
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $410,000 in funding to the University of Chicago to conduct research on bacterial secretion systems using cryo-electron tomography. The key objectives are to: Investigate the assembly, disassembly, and function of bacterial flagellar motors (type III secretion systems) and type IV secretion systems, which are involved in...
- This Project Grant award of $440,000.00 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), is focused on two key research areas: Developing a quantitative understanding of the processes involved when contractile injection systems (e.g. phage tails, tailocins, Type VI secretion systems) breach bacterial cell envelopes. This knowledge will be applied to the design and retargeting of R-type pyocins...
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $408,375 Project Grant to the University of Alabama at Birmingham (UAB). The grant, with a performance period from September 1, 2025 to August 31, 2030, aims to investigate the fundamental mechanisms underlying the production, regulation, and function of microbial appendages, such as flagella and pili, and to utilize this knowledge to design...
- This federal Project Grant award of $377,500.00 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research to explore the mechanisms by which bacteriophages (viruses that infect bacteria) interact with bacterial glycoconjugates (carbohydrate-containing molecules). The project aims to investigate the strategies used by certain phages to replace canonical DNA bases with non-canonical bases, as well...
- This federal Project Grant award of $401,253 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports research to elucidate novel cyclic nucleotide signaling pathways and their physiological effects in bacteria. The research program will synthesize chemical tools and use in vitro and in cellulo techniques to investigate the effects of 2',3'-cyclic nucleotide monophosphates (2',3'-cNMPs) on bacterial...
- This federal Project Grant award for $406,652 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to elucidate the fundamental aspects of oleate hydratase (OHYA) biology and its role in lipid-protein interactions across microbial communities. The research will investigate how OHYA acquires unsaturated fatty acid substrates from cell membranes, how bacteria utilize OHYA and distribute hydroxy fatty...
- This federal Project Grant award of $294,060 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research to understand biophysical principles of cellular organization at two scales: bacterial communities and intracellular biomolecular condensates. The research aims to elucidate how bacterial quorum sensing operates in natural environments, including the influence of other species, and to investigate...
- This federal Project Grant award of $556,510 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports a research program focused on understanding the molecular mechanisms and evolution of the rhoptry secretion system in unicellular eukaryotes within the Alveolata superphylum, including apicomplexan parasites and non-pathogenic ciliates. The research aims to: 1) determine the conserved basic architecture...
- The National Institute of General Medical Sciences (NIGMS) awarded a 5-year, $433,459 Project Grant under CFDA 93.859 (Biomedical Research and Research Training) to the University of Kansas Center for Research Inc. The grant supports fundamental research to expand the understanding of quorum sensing - a type of cell-cell communication used by bacteria, including many pathogens, to coordinate group behaviors. The research will combine laboratory models with molecular genetic and genomic...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $506,105.00 to The Medical College of Wisconsin, Inc. to conduct research on the functional dynamics of essential bacterial proteins and develop transformative electron paramagnetic resonance (EPR) spectroscopy technologies. The research aims to gain detailed knowledge of protein structure and dynamics to aid in...