Project Grant 2443851

Award Date 2/1/25
Completion Date 1/31/30
Dollars Obligated $150K
Federal Agency
Division of Physics
Federal Grant Program
47.049
Assistance Type
Project Grant
Place of Performance
La Jolla, CA 92093, USA
Similar Awards
This $253,154 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports research at the University of California, San Diego (UCSD) to elucidate the physical mechanisms governing how avian embryos control their dynamic geometry during the critical developmental stage of gastrulation. The principal investigator will leverage advanced cell-level data and develop mathematical models to understand how the collective behaviors...
This Project Grant award, valued at $257,591, was provided by the National Science Foundation's (NSF) Division of Mathematical Sciences under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The award supports a collaborative research project between the University of California-Riverside and the University of Notre Dame to develop data-driven, multi-scale mathematical and computational models for investigating the critical signaling pathways and biophysical mechanisms...
This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program provides $227,747 to the Regents of the University of California at Riverside, a Hispanic-serving research institution, for a collaborative research project investigating morphogenesis and organ development. The key objectives of the funded research are to develop new multiscale mathematical and computational models to simulate multicellular wing disc morphogenesis in...
The National Science Foundation awarded a $192,089 Project Grant to the University of Chicago under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) for research titled "Co-Dynamics of Contraction and Adhesion in Animal Morphogenesis." The three-year award beginning March 1, 2022 will support research using advanced microscopy, genetic and biophysical manipulations, and mathematical modeling to gain new insights into the mechanisms governing rapid tissue...
This $769,770 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) will fund research at Ball State University from September 2022 through August 2025. The research aims to develop rigorous mathematical models describing the coordinated changes in form and function that occur through ontogeny in arboreal lizards. Researchers will conduct biomechanical experiments and morphological analysis on mourning geckos and three additional arboreal...
This $995,173 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program is designed to broaden the understanding of muscle formation (myogenesis) in birds and mammals. The project will use a novel approach for analyzing gene expression patterns to advance the understanding of developmental mechanisms, with a primary focus on the chicken as a species of importance to U.S. and global food security. The award will support the advancement of...
This National Science Foundation project grant of $1,011,518 supports collaborative research between the University of California, San Diego and the State of California Controller's Office to discover the principles of active self-organization in the differentiating genome. The award period is from July 1, 2022 through June 30, 2026 under the Mathematical and Physical Sciences program (CFDA 47.049). The project will integrate state-of-the-art live cell experiments with multiscale mathematical...
This National Science Foundation (NSF) Mathematical and Physical Sciences (CFDA 47.049) Project Grant award of $330,000 supports theoretical and computational research by the University of California, Merced to describe and understand the behavior of biologically-inspired active solids. The research aims to create models that combine mechanical and chemical factors to investigate the unique shape changes and self-organization phenomena possible in active solids, such as those found in cell...
The National Science Foundation awarded Northwestern University $256,961 under the Biological Sciences federal grant program (CFDA 47.074) to construct a single-cell mechanical atlas describing mechanical stresses during gastrulation in ascidian embryos. The collaborative US-France project aims to deepen understanding of how living matter generates and controls mechanical forces during development. Investigators will measure mechanical stresses in 3D and at single-cell resolution over time in...
This Project Grant award from the National Science Foundation (NSF) Division of Civil, Mechanical, and Manufacturing Innovation provides $390,593 to Syracuse University for research on the mechanoregulation of amnion patterning through activation of bone morphogenetic protein signaling. The 3-year project aims to study amnion development using a stem cell-derived human development model, with the goal of advancing knowledge in early human development and enabling the rational design of 3D stem...

This Project Grant award, valued at $149,926, was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The award supports research by the University of California, San Diego (UC San Diego) to elucidate the principles governing how avian embryos regulate their dynamic geometry during gastrulation, a crucial developmental stage.

The research aims to develop mathematical models that integrate cell-scale behaviors and mechanical properties to understand how tens of thousands of cells self-organize to generate the embryo's emergent shape and size. This work will shed light on the role of fundamental cell behaviors in controlling embryo geometry, generate new testable predictions, and establish a framework for understanding how mechanical information propagates and is processed in living systems. The research also includes an educational program providing K-12 to graduate students opportunities to explore the physics of living systems. This award, spanning from February 2025 to January 2030, reflects NSF's mission to promote scientific progress and strengthen the nation's scientific enterprise.

Generated 7/15/25, 3:06 AM