The National Institute of General Medical Sciences (NIGMS) has awarded a $439,992 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to Iowa State University of Science and Technology to develop synthetic mimics of enzymes and antibodies for binding and hydrolysis of complex biological targets such as glycans, peptides, and post-translationally modified proteins. The project, titled "Mimics of Enzymes and Antibodies for Glycans and Other Biological Targets," aims to create highly selective and efficient molecularly imprinted nanoparticles (MINPs) that can serve as artificial enzymes and antibody mimics. The research seeks to enable new applications for controlling protein modifications, elucidating cell signaling, and targeted degradation of amyloid proteins. The award period runs from April 15, 2025 to March 31, 2030.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $440.0k | 4/15/25 |