Project Grant R35GM156309
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $1,173,990 Project Grant to the University of Wisconsin-Madison to provide predoctoral-level training in interdisciplinary quantitative research at the interface between biological and physical disciplines. The goal of the Molecular Biophysics Training Program (MBTP) is to recruit cohorts of students from diverse biological and physical science...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $372,100 to the University of Wisconsin - Madison to develop novel "mechanoimaging" technologies that can measure and program piconewton-scale mechanical forces exerted by individual cell receptors in viscoelastic biomaterials. The goal is to quantify how cells, including fibroblasts, cancer cells, and T cells, physically...
- The National Science Foundation (NSF) awarded a $626,831 Project Grant under its Biological Sciences program (CFDA 47.074) to the University of Wisconsin-Milwaukee (UWM) to conduct collaborative research on the molecular mechanisms behind how certain bacteria use light-sensing proteins called phytochromes to regulate essential developmental processes. The project aims to use advanced structural biology techniques like cryo-electron microscopy and time-resolved X-ray crystallography to study...
- The University of Wisconsin - Madison, operating as Research and Sponsored Programs under the University of Wisconsin System, was awarded a $510,959 Project Grant by the National Science Foundation (NSF) Engineering program (CFDA 47.041) to develop computational methods to design nanoparticles for use with a variety of cell types. The project aims to combine all-atom molecular dynamics simulations, topological data analysis, and machine learning to predict the binding of proteins to...
- The National Science Foundation awarded $357,323 under the Engineering (47.041) federal grant program to the University of Wisconsin-Madison for the project "Driving Quantum Systems with Classical Fields." Over a three-year period ending August 2025, the University will develop state-of-the-art simulation software to analyze how electrons in nanoscale devices interact with classical light and sound waves. The University will integrate recent advances in computational electromagnetics...
- The federal Project Grant award of $394,000 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), is funding research conducted by Northeastern University to develop novel quantum sensor-enhanced magnetic resonance techniques. The key objectives are to improve the compatibility of nitrogen-vacancy (NV) center quantum sensors with biological systems and leverage their unique properties to enhance magnetic...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $495,117 to the University of Wisconsin System for a project titled "Accessing the Hidden Biosynthetic Capabilities of Fungi". The project aims to advance natural product discovery from filamentous fungi by: (1) elucidating the products of fungal gene clusters encoding unusual enzymes and chemistries, (2) examining how...
- The National Institute of General Medical Sciences (NIGMS) awarded a $1,316,016 Project Grant under CFDA Program 93.859 (Biomedical Research and Research Training) to the University of California, Irvine (UCI) to develop a novel biosensing platform for label-free, single-molecule detection at ultra-high speeds using metasurface-enhanced coherent Raman scattering. The 4-year project, running from September 2025 to August 2029, aims to overcome fundamental speed limitations in surface-enhanced...
- The U.S. National Institute of General Medical Sciences (NIGMS), through the Biomedical Research and Research Training federal grant program (CFDA 93.859), awarded a $432,834 Project Grant to the Board of Regents of the University of Nebraska on April 15, 2025. The grant supports the development of an "enzyme-free, label-free quantitative microarray technology" to detect and quantify target nucleic acids, such as microRNA, with high sensitivity down to the attomolar (10^-18 M) range....
- The University of Wisconsin-Madison received a $1,827,200 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to develop a "Continuous Evolution Platform for Cyclic Peptide Discovery". The goal of this 4-year grant, awarded on September 1, 2025, is to advance the state-of-the-art in cellular cyclic peptide discovery by creating a new platform based on phage-assisted continuous evolution....
The University of Wisconsin System was awarded a $450,430 Project Grant by the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), to develop nanophotonic devices for quantum-enhanced biological applications. The project aims to leverage quantum mechanical principles to achieve unprecedented precision and accuracy in sensing and manipulating intracellular processes, such as gene expression, protein, and metabolic pathways. Specifically, the research will focus on two thrusts: 1) implementing photonic cavities to achieve vibrational strong coupling between infrared resonances and biomolecules, enabling non-invasive regulation of intracellular chemical processes, and 2) demonstrating quantum-enhanced nanophotonic biosensing techniques. The project period runs from August 1, 2025, to May 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $450.4k | 7/30/25 |