This $278,848 Project Grant award from the National Institute of General Medical Sciences (CFDA 93.859 Biomedical Research and Research Training program) supports Brigham Young University's research to expand the capabilities and usage of the TELSAM protein crystallization chaperone. The key goals are to: 1) provide experimentally validated guiding principles for using TELSAM, 2) demonstrate TELSAM's general efficacy through successful use cases, and 3) explore TELSAM's applications and limitations for accelerating structure determination of biotechnology and disease-relevant proteins, drugs, and biologics. This 5-year project aims to revolutionize protein crystallization methods, enabling more effective disease treatments and reduced healthcare costs by overcoming the bottleneck of protein structure determination. The award will also help develop undergraduate and graduate students, including underrepresented minorities, into excellent biochemists through hands-on research participation.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $278.8k | 9/10/24 |