This Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) provides $2,419,326 to Virginia Polytechnic Institute & State University (Virginia Tech) to conduct longitudinal research on neurobehavioral and psychosocial predictors of health risk behaviors (HRBs) in adolescence and young adulthood. The study aims to: (1) assess longitudinal associations between valuation/control systems and HRBs from adolescence to young adulthood;...
This $181,040 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to create an immersive training experience to study the genetic etiology of substance use disorders (SUDs). The award recipient, Yale University, will leverage the Million Veteran Program (MVP) biobank to: (1) model patterns of SUD co-occurrence and substance co-use, (2) utilize electronic health record data and toxicology results to provide...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $357,613 to Yale University to conduct research aimed at improving the understanding of the genetic mechanisms underlying substance use disorders (SUDs). The key objectives of this 2-year project are to: 1) leverage large-scale whole-genome sequencing (WGS) datasets to identify novel rare and common genetic variants associated with SUDs and recover...
This federal Cooperative Agreement award of $2,094,403.00 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will support research to identify genes that affect behaviors associated with substance use disorders (SUDs). The University of California, Los Angeles (UCLA) will conduct a novel mechanism-to-gene strategy to genetically map circuit-driven behavioral outputs related to anxiety and SUDs. The key research activities...
This Project Grant award of $207,910 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports a 3-year training program for a graduate student at the University of Michigan to research shared neurobiological mechanisms that can confer vulnerability to addiction and comorbid psychiatric disorders such as post-traumatic stress disorder. The project will utilize chemogenetic and fiber photometry techniques to examine the...
The National Institute on Drug Abuse (NIDA) awarded a $267,696 Project Grant under CFDA 93.279 - Drug Use and Addiction Research Programs to the University of Massachusetts Lowell (UML), a minority-serving institution, for the project "Enhancing Opportunities for Addiction Research in the Merrimack Valley." The project aims to expand UML's existing Public Health Informatics and Technology (PHIT) program by creating a new PHIT-AR (Addiction Research) track. This will recruit diverse...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will fund research to study the neurogenetic mechanisms underlying nicotine and cannabis addiction. The $175,888 award, effective September 1, 2024 through August 31, 2028, will enable the development of novel transcriptome-connectome analysis methods to identify genes associated with changes in brain functional connectivity related to addiction. The...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the federal Drug Use and Addiction Research Programs (CFDA 93.279), will provide $391,833 to the Icahn School of Medicine at Mount Sinai to conduct preparatory research activities. The goal is to establish the feasibility and validity for a future project examining the impact of juvenile social isolation on the maturation of the prefrontal cortex circuit and substance use disorder-relevant behaviors. The preparatory...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will support a multivariate genome-wide association analysis of opioid-related traits in a diverse population of over 500,000 individuals. The $715,238 award, effective January 15, 2025 through November 30, 2029, will enable researchers at the University of California, San Diego to investigate the genetic basis of pre-addiction opioid use stages,...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports research to develop a translational rat model of the neonatal intensive care unit (NICU) experience and its impacts on substance use disorder risk. The $368,315 award to the Georgia State University Research Foundation will: 1) design and test a model combining early pain, resource scarcity, and separation from caregivers to mimic key aspects of...