This Project Grant award from the National Institute on Drug Abuse (NIDA), under the federal Drug Use and Addiction Research Programs (CFDA 93.279), will support a $346,911 cross-species research study to identify early life environmental and genetic risk factors for substance use disorders (SUDs). The key objectives are to: 1) determine how early life environment influences neurocognitive development and its relationship to adult impulsivity behaviors; 2) identify genomic networks associated...
This $2,811,343 Project Grant awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) supports the Center for Genetics, Genomics, and Epigenetics of Substance Use Disorders in Outbred Rats. The primary goals are to provide critical core services to a community of researchers using outbred heterogeneous stock (HS) rats to study the genetic basis of individual differences in vulnerability to substance use disorders. Key services...
This Cooperative Agreement award from the National Institute on Drug Abuse (NIDA), under the federal Drug Use and Addiction Research Programs (CFDA 93.279), provides $944,888 to the Seattle Children's Research Institute to conduct a deep analysis of the transcriptome in rats to understand the genetics of substance use disorders. The 5-year project, starting July 1, 2025, will produce an unprecedented atlas of variation in the rat transcriptome as a mediator of substance use disorder-relevant...
This federal Project Grant award of $360,000.00 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to develop methods for assessing the effects of social isolation and loneliness during early life on neurocognitive function and addictive behavior in adolescent and adult rats. The research team from Old Dominion University (ODU) and the ODU Research Foundation (Odurf) will employ a rat model comparing the impacts of single...
This Project Grant award of $1,315,596 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to investigate the effects of maternal exposure to electronic nicotine delivery system (ENDS) aerosols during pregnancy on addiction-related behaviors and neurobiology in offspring. The primary objectives are to examine the impacts of maternal ENDS aerosol exposure on measures of impulsivity, nicotine abuse liability, and function of...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $118,656 to the Ponce Medical School Foundation Inc. in Puerto Rico. The funding will support research to investigate the influence of fear conditioning and cocaine exposure on cocaine-seeking behavior in adult rats, with a focus on analyzing the neurophysiological changes in the prelimbic cortex-nucleus accumbens core circuitry. The project aims...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will support a research project entitled "Optimizing Developmental Outcomes in Early Childhood After Neonatal Opioid Withdrawal Syndrome." The $180,059 award, effective August 1, 2024, will fund a 5-year longitudinal study to assess the independent and moderating effects of positive childhood experiences (PCEs) and adverse childhood experiences...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the federal Drug Use and Addiction Research Programs (CFDA 93.279), is funding a study on age and sex differences in reward responses after punishment in rodent models of drug use. The $159,625 award to the University of Texas at Austin covers a project period from July 1, 2025 to June 30, 2027. The goal of the research is to examine if punishment can deter future drug use, particularly during adolescence when...
This $161,664 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will support the development of a behavioral arena and computational framework to study social behaviors in Lake Malawi cichlids. The project aims to create tools to track animals and measure social behavioral dynamics within a natural environment mimicking context, including factors like hierarchy and male displays. This work will generate new...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $149,000 in funding to the University of Oregon to conduct a longitudinal study examining the developmental trajectories of autonomic reactivity and regulation in children exposed prenatally to cannabis and tobacco. The key objectives of the study are to: 1) examine changes in parasympathetic nervous system functioning from infancy to early...