Project Grant R33AG104101
- The National Institute on Aging awarded the University of Southern California $710,296 on September 1, 2026, under the Aging Research program (CFDA 93.866) to expand research infrastructure for the Interplay of Genes and Environment Across Multiple Studies (IGEMS) Consortium. The consortium integrates twin studies from five countries, focusing on adult development and aging, and has harmonized data from over 126,000 individuals to examine gene-environment interplay in aging, particularly...
- The National Institute on Aging awarded The University of Chicago $1,460,509 on July 1, 2026, under the Aging Research program (CFDA 93.866) to conduct a longitudinal study examining how environmental exposures contribute to Alzheimer's disease and related dementias among older US adults. The project, titled "Experiences, Exposures, and Alzheimer's Disease: Longitudinal Study of Olfaction, Cognition, and Metabolism in Older US Adults (NSHAP Exposome)," will enrich data collection...
- The National Institute on Aging awarded the University of California, Los Angeles $623,176 on September 1, 2026, under the Aging Research program (CFDA 93.866) to conduct research on modifiable risk factors for Alzheimer's disease and related dementias among individuals aged 90 and older. The research triangulates evidence across four data sources—the LifeAfter90 Study (1,397 participants, all aged 90), the 90+ Study (1,630 participants, all aged 90), the Health and Retirement Study (3,359...
- The National Institute on Aging awarded the University of Southern California $695,789 on January 1, 2026, under the Aging Research program (CFDA 93.866) to develop HGEA-NET, a multiscale computational model of the hippocampus that integrates cell type-specific gene expression and connectivity data to understand how progressive neurodegeneration of vulnerable neuronal populations leads to hippocampal network dysfunction and cognitive decline in Alzheimer's disease. The project builds on USC's...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of Southern California $4,055,366 under the Aging Research program (CFDA 93.866) to conduct a four-year research project examining the impact of circulating endocrine disrupting toxicants on cognition, brain activity, and Alzheimer's disease (AD) biomarkers across the menopausal transition. The project, which commenced on September 15, 2025, and concludes August 31, 2029, addresses a critical gap...
- The National Institute on Aging awarded Drexel University $1,306,728 under the Aging Research program (CFDA 93.866) on August 1, 2026, to conduct a longitudinal, multi-site study examining how individual lifestyle, social circumstances, and neighborhood-level factors influence physical functioning trajectories in older adults across population subgroups and U.S. regions. The research leverages over 30 years of longitudinal data from the Multi-Ethnic Study of Atherosclerosis (MESA) cohort and...
- The National Institute on Aging awarded $1.669 million to American Institutes For Research In The Behavioral Sciences on September 15, 2025, under the Aging Research program (CFDA 93.866) to develop a comprehensive residential address history for Project Talent participants and geocode addresses to support research on neighborhood characteristics and cognitive health outcomes related to Alzheimer's disease and related dementias. The project will identify Project Talent participants in the...
- The National Institute on Aging awarded the National Bureau of Economic Research Inc. $427,646 on September 1, 2026, under the Aging Research program (CFDA 93.866) to trace mid-life mortality of birth cohorts born approximately 1940–1960 in the United States by place, time, and family factors. The research combines large-scale administrative datasets—the Numident, Bureau of the Census Numident Mortality Detail file, and Mortality Linkage Project data, containing more than 3.5 million death...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded $674,088 to The General Hospital Corporation (doing business as Massachusetts General Hospital) on September 1, 2026, under the Aging Research program (CFDA 93.866) to investigate how environmental and psychosocial exposures shape Alzheimer's disease and related dementias outcomes. The project introduces a novel exposome-health outcomes framework tailored to real-world data, particularly Medicare...
- The National Institute on Aging awarded the Regents of the University of Michigan $1,703,843 on April 1, 2026, under the Aging Research program (CFDA 93.866) to generate prospective environmental chemical exposure data from stored biospecimens in the Health and Retirement Study cohort and examine associations between chemical and social exposures and Alzheimer's disease and related dementias (ADRD). The project performs state-of-the-art non-targeted analysis to measure chemical levels...
The National Institute on Aging awarded the University of Southern California $586,743 on September 4, 2026, under the Aging Research program (CFDA 93.866) to develop the Gateway to American Aging Data (GAMA), a research infrastructure designed to accelerate life course research on how modifiable environmental exposures shape later-life health outcomes. GAMA will harmonize survey data across five nationally representative U.S. cohorts: the Panel Study of Income Dynamics (PSID), National Longitudinal Survey of Youth 1979 Cohort (NLSY79), Health and Retirement Study (HRS), National Social Life, Health and Aging Project (NSHAP), and National Health and Aging Trends Study (NHATS). The project will link common harmonized environmental exposure data—including PM2.5, NO2, ozone, and greenspace—to survey participants using geographic residential information. The infrastructure will enable analysis of how environmental exposures during childhood, mid-life, and late-life shape later-life health. The project will demonstrate the value of pooled data by examining effects of low wage earning across the full life course on disablement progression risk in later life, and by evaluating the added scientific value of common environmental exposome data across multiple cohorts. Work is performed in Los Angeles, California with a period of performance from September 4, 2026, through May 31, 2031. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $586.7k | 9/3/26 |