Project Grant R25AG086101
- The University of Kentucky Research Foundation was awarded a $418,309 Project Grant by the National Institute on Aging (NIA) on August 15, 2025 under the Aging Research Federal Grant Program (CFDA 93.866) to establish the Kentucky Postbaccalaureate Alzheimer's Disease (KYPAD) Research Education Program. This program will provide an intensive research experience for recent biomedical and behavioral science graduates to prepare them for advanced degree programs focused on Alzheimer's disease and...
- This federal Project Grant award of $428,410 was provided by the National Institute on Aging (NIA) under the Aging Research Federal Grant Program (CFDA 93.866). The grant is funding the Research and Education in Alzheimer's Disease and Dementias Initiative for Equity (READDIE) program at the Wake Forest University School of Medicine (WFUSM). The READDIE program is designed to facilitate postbaccalaureate trainees' entry into and completion of PhD programs in Alzheimer's disease and related...
- The University of South Florida (USF) was awarded a $3,297,926 project grant from the National Institute on Aging (CFDA 93.866 - Aging Research) to develop novel biomaterials that can prevent, halt, and potentially cure Alzheimer's disease (AD). The objective of this 4-year project is to advance USF's preliminary work on designing peptide hybrid biomaterials that can stabilize the helical conformation of the amyloid-beta (Aβ) peptide, thereby shifting the equilibrium of Aβ aggregation away...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $372,904 to The University of Texas Health Science Center at San Antonio to advance cross-national research on aging and cognitive function. The 5-year grant, awarded on September 20, 2025, supports an annual program that recruits, trains, and mentors 16 post-graduate participants dedicated to mastering Down syndrome (DS) clinical research. The program offers hands-on DS clinical...
- This federal Project Grant award for $2,557,260 from the National Institute on Aging (CFDA 93.866 Aging Research program) will fund a study titled "Lifecourse Predictors and Mechanisms of Early Clinical ADRD among Black and White Adults in their Sixties". The study aims to investigate the transition from midlife to early late-life and identify the earliest manifestations of Alzheimer's disease (AD) and Alzheimer's disease-related disorders (ADRD) in a diverse population. The research...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $454,271 to Florida Atlantic University to investigate the role of amyloid precursor protein (APP) and cholesterol homeostasis in synaptic dysfunction and neurodegeneration related to Alzheimer's disease (AD). The research aims to use human neurons derived from induced pluripotent stem cells (hiNs) to systematically study how mutations affecting APP distribution, trafficking, and interaction...
- This federal Project Grant award for $528,876, provided by the National Institute on Aging (CFDA 93.866 Aging Research), supports research to investigate the cis- and trans-genetic regulation of brain transcriptomics and proteomics associated with Alzheimer's disease (AD) and AD-related dementias (ADRD). The key goals of the project are to: Estimate genome-wide cis- and trans-acting quantitative trait loci (QTLs) effects for transcriptome-wide genes and proteome-wide proteins across 4 brain...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $848,286 to the University of South Florida to conduct research on the role of N6-methyladenosine (m6A) RNA modifications in Alzheimer's disease (AD). The key objectives are to: 1) Create a high-resolution map of m6A sites in the brains of older adults, 2) Identify specific m6A alterations associated with AD and its clinical/pathological features, and 3) Elucidate how m6A dysregulation may...
- This federal Project Grant award of $307,000.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to conduct a single, highly powered study to identify memory processes that are most sensitive to the asymptomatic, preclinical stage of Alzheimer's disease (AD) pathology. The study combines a continuous report item-location associative memory task with advanced behavioral and neural modeling to estimate subtle changes in memory precision that may differentiate healthy...
- This $4,444,978 federal Project Grant award, issued by the National Institute on Aging (CFDA 93.866 Aging Research program), supports research to characterize cognitive reserve and identify modifiable factors that promote cognitive reserve and resilience to Alzheimer's disease and related dementias (ADRD) among older adults in India, with a focus on those who lack formal education. The project aims to: 1) compare brain pathology measures and their contributions to cognition between older...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $366,985 to the University of South Florida (USF) to develop the USF Health Expanding Research in AD/ADRD (ERA) Post-Baccalaureate Research Education Program (PREP). The program aims to train a cohort of post-baccalaureate students with limited research experience to transition into Alzheimer's disease and related dementias (AD/ADRD) research-focused doctoral programs. Led by Professors Paula C. Bickford and Gopal Thinakaran, the 5-year program will provide intensive research experience and mentorship to recruit and prepare students for PhD and MD/PhD programs in AD/ADRD research. This initiative leverages USF's strong research capabilities in molecular, cellular, pathological, clinical, and regenerative aspects of AD/ADRD to expand the pipeline of future researchers dedicated to the prevention, treatment, and cure of these disorders.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $367.0k | 9/3/25 |