Project Grant R24OD040049
- Federal Project Grant Award Summary Pennsylvania State University, operating as Penn State Milton S. Hershey Medical Center, received a $863,982 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) on August 15, 2025, with a completion date of July 31, 2029. The award funds development of a comprehensive 3D zebrafish microanatomical and gene expression atlas designed to advance disease modeling...
- Federal Project Grant Summary The University of Colorado-Denver received a $779,657 Project Grant award from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) on July 15, 2025, with completion anticipated by June 30, 2029. This award supports the establishment and expansion of community-accessible resources for site-directed transgenesis in zebrafish, a critical research model for studying vertebrate development, regeneration, and...
- Federal Grant Award Summary Colorado State University's Sponsored Programs Division received a $778,241 Project Grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) effective August 1, 2025, through July 31, 2029. This award supports the generation and validation of recombinant monoclonal antibodies and antibody-based biosensors specifically designed for the zebrafish research community. The project addresses a critical...
- Federal Grant Award Summary The University of Pennsylvania received a $573,005 Project Grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) on May 15, 2026, to acquire a LUMICKS AVIDION Cell Avidity Analyzer. This high-throughput platform enables quantitative measurement of cell-cell interaction avidity, addressing a critical institutional gap in systematically assessing the efficacy of adoptive cellular immunotherapies such...
- Federal Project Grant Summary Duke University's Office of Research Administration is executing a research infrastructure project funded by the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351). This $444,125 award, which commenced July 1, 2026 and concludes June 30, 2028, supports the development of zebrafish tools for investigating enteroendocrine hormone biology. The project focuses on characterizing the structure and function...
- Federal Project Grant Award Summary The National Science Foundation (NSF), Division of Molecular and Cellular Biosciences, awarded $622,842 to the University of Pennsylvania on May 1, 2026, under the Biological Sciences program (CFDA 47.074) to support collaborative research on zygotic genome activation (ZGA) in fruit fly embryos. This project will deliver research outputs investigating how cells measure and respond to changes in the nuclear-to-cytoplasmic (N/C) ratio to control the timing of...
- Federal Project Grant Award Summary The National Institutes of Health Office of the Director awarded the University of Pennsylvania $405,787 under the Research Infrastructure Programs (CFDA 93.351) for the acquisition and installation of an Asymmetric Field Flow Fractionation-Multiangle Light Scattering (AF4-MALS) analytical system at the Johnson Foundation Structural Biology and Biophysics Core. The integrated instrument combines field-flow fractionation technology for non-destructive...
- Federal Grant Award Summary The University of Pennsylvania received a $688,506 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective April 1, 2026 through March 31, 2031. The award supports integrative genomic analyses designed to advance understanding of human evolution and complex traits in African populations through a comprehensive multi-omics approach. The research will generate...
- Federal Project Grant Award Summary Cornell University received a $432,204 Project Grant from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) beginning July 1, 2026 and concluding June 30, 2028. The award supports development of a novel tissue-specific protein labeling technique for use in Drosophila disease models. The primary deliverable is the establishment of a split-intein HaloTag (SIH) system that combines HaloTag...
- Federal Project Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded the University of Pennsylvania $616,897 on August 8, 2025, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop synthetic intracellular compartments capable of rewiring inflammatory signaling pathways in immune cells. The project, which extends through July 31, 2027, addresses a critical challenge in...
The University of Pennsylvania received $812,443 in federal funding from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to develop an engineered protein tag resource for live imaging and functional studies in zebrafish. The award, effective July 1, 2026 through March 31, 2030, encompasses development of a computational software package designed to identify optimal epitope tag integration sites within protein sequences using conservation analysis and machine-learning-based protein structure prediction. The software will be validated empirically and made freely available as a web-based tool to the research community. Additionally, the project will generate approximately 60 epitope-tagged zebrafish lines of genes identified as high-interest by the zebrafish research community and relevant to human health and disease. The deliverables include continued refinement of the user-friendly software platform for researchers worldwide and experimental validation of a newly developed ALFA epitope tag methodology to investigate protein function in zebrafish models. By providing both computational tools and validated transgenic zebrafish resources, this project addresses a critical gap in the availability of functional protein-specific resources for vertebrate genetic research, enabling broader investigator access to multifunctional epitope-tagged organisms without requiring direct development of antibody resources.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $812.4k | 6/23/26 |