Project Grant R24OD039886
- Federal Project Grant Award Summary The Medical College of Wisconsin, Inc. received a $655,441 project grant award dated August 15, 2025, through the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351). The award funds the Cre-Driver Rat Resource Project (R24), which will develop, validate, and distribute transgenic rat models to the biomedical research community through August 31, 2029. The project leverages existing institutional...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded The Medical College of Wisconsin, Inc. a Project Grant of $432,625 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop animal models and resources for preclinical lower urinary tract research. The award, effective August 6, 2025, through July 31, 2027, supports the creation of a comprehensive dataset measuring urological...
- Federal Project Grant Award Summary The National Institutes of Health (NIH) Office of the Director awarded $230,250 through the Research Infrastructure Programs (CFDA 93.351) to the University of Nebraska Medical Center for the development of transgenic mouse model resources expressing red fluorescence-based genetically encoded indicators. This two-year project, which commenced July 1, 2025 and concludes June 30, 2027, addresses critical limitations of existing green fluorescent protein...
- Federal Project Grant Award Summary The Medical College of Wisconsin, Inc. received a $234,000 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective July 1, 2026, through June 30, 2028. The award funds a single-cell dissection study investigating cellular and transcriptional dynamics driving post-transplant relapse in myelodysplastic syndromes (MDS) following allogeneic hematopoietic cell...
- Federal Grant Award Summary The National Institutes of Health Office of the Director awarded University of Wisconsin–Madison a $1.49 million Project Grant under the Trans-NIH Research Support program (CFDA 93.310) on September 16, 2025, with a completion date of August 31, 2027. This research initiative focuses on developing and characterizing humanized mouse models to study Down syndrome immune responses, specifically addressing the immune dysregulation associated with trisomy 21. The project...
- Federal Project Grant Award Summary Massachusetts General Hospital's Research Management Division received an $800,824 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) on July 15, 2026, with a completion date of April 30, 2030. The award supports the development of next-generation preclinical zebrafish xenograft models for human cell and tissue transplantation studies. The primary deliverables...
- Federal Grant Award Summary The National Institutes of Health (NIH) Office of the Director awarded $418,641 to the University of Wisconsin–Madison under the Research Infrastructure Programs (CFDA 93.351) on July 1, 2026, for a two-year project extending through June 30, 2028. This Project Grant supports the development and application of a genomic authentication pipeline designed to validate laboratory stocks of Drosophila melanogaster (fruit flies), a critical model organism in biomedical...
- Federal Project Grant Summary The University of Colorado-Denver received a $779,657 Project Grant award from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) on July 15, 2025, with completion anticipated by June 30, 2029. This award supports the establishment and expansion of community-accessible resources for site-directed transgenesis in zebrafish, a critical research model for studying vertebrate development, regeneration, and...
- Federal Project Grant Award Summary The Medical College of Wisconsin, Inc. received a $722,631 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective June 17, 2026 through February 28, 2031. This R01 research project aims to validate the pathogenicity of 23 mitochondrial DNA (mtDNA) variants of uncertain significance (VUS) associated with primary...
- Federal Grant Award Summary The Medical College of Wisconsin, Inc. received a $351,840 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded June 16, 2026, with completion targeted for May 31, 2031. This research initiative develops and validates viral-mediated optogenetic techniques for peripheral nerve stimulation to restore motor function,...
Summary The Medical College of Wisconsin, Inc. received a $777,972 Project Grant award from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to establish and maintain the Hybrid Rat Discovery Panel (HRDP) as a renewable genetic resource for clinical translation research. The award, effective July 15, 2026 through July 14, 2030, supports the continuation and expansion of the HRDP as a well-characterized genetic reference population comprising 33 classic inbred rat strains, 30 HXB/BXH recombinant inbred strains, and 34 FXLE/LEXF recombinant inbred strains. The project delivers living colonies of these rat strains to the research community along with comprehensive genomic, transcriptomic, and curated phenotypic datasets to support investigations across complex disease areas including hypertension, stroke, diabetes, cancer, and arthritis. The funded initiative addresses four specific aims: maintaining the HRDP as living colonies, extending genomic resources for rigor and reproducibility, developing user-selection tools to guide strain identification, and expanding distribution channels to broaden researcher access. Through outreach and pilot program opportunities, the HRDP enables investigators to evaluate phenotypic distributions using small cohorts before committing to larger studies. The resource provides multiple access pathways including individual disease models, a characterized 8-strain mini-HRDP subset, heterogeneous stock founder "best match" strains, and the full panel, ensuring broad utility across the biomedical research community.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $778.0k | 7/16/26 |