Project Grant R01NS142067
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Washington University a Project Grant totaling $567,037 beginning August 1, 2025, through July 31, 2030, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This award supports research to characterize the synchronous relationship between peripheral nerve post-injury activity and brain plasticity following traumatic peripheral nerve...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the Regents of the University of Michigan a Project Grant totaling $531,478 under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award, effective August 1, 2025, through July 31, 2030, supports fundamental research investigating the immune metabolic mechanisms underlying peripheral nervous system (PNS) degeneration and regeneration...
- Federal Grant Award Summary The Medical College of Wisconsin, Inc. received a $413,808 Project Grant from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) effective August 1, 2026, through July 31, 2028. The award supports research to develop and validate a wireless cranial stimulation protocol using the FDA-approved Responsive Neurostimulation (RNS) System to induce neuroplasticity in glioma patients. The primary objective is to enable safer and more...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $470,293 to The Research Foundation For The State University of New York (SUNY at Binghamton) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective July 1, 2025, through June 30, 2027. This Project Grant funds research aimed at identifying and characterizing the electrophysiological features of spinal motor neurons during...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $1,110,530 to The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. on March 5, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This Project Grant (R01 mechanism) supports neuroscience research examining neural plasticity and myelin dynamics following unilateral denervation injuries, with a...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a $232,938 Project Grant (R21) effective February 17, 2026, through January 31, 2028, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This award funds research to generate critical knowledge regarding neuronal membrane proteasome (NMP)-derived peptide signaling in the peripheral nervous system (PNS). The...
- Federal Project Grant Award Summary The Medical College of Wisconsin, Inc. received a $751,694 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective April 21, 2026, with completion targeted for February 28, 2031. This award funds preclinical research to optimize tibial nerve stimulation (TNS) therapy for treating neurogenic bladder dysfunction in...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $494,240 to the University of Wisconsin-Madison, with an award date of February 16, 2026, and a completion date of January 31, 2031. Under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), this research project investigates microRNA (miRNA) degradation mechanisms in post-stroke brain tissue. Specifically, the research...
- Federal Project Grant Award Summary The University of Michigan received a $556,525 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective June 1, 2025 through April 30, 2030. The award supports the development and dissemination of artifact-free micro-light-emitting diode (micro-LED) optoelectrode platforms designed to advance neural circuit...
- Federal Project Grant Award Summary The University of Miami, through its Office of Research Administration within the School of Medicine, received a $368,695 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective June 1, 2026, through May 31, 2027. The award supports research aimed at identifying and developing small-molecule inhibitors...
The Medical College of Wisconsin, Inc. received a $351,840 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective June 16, 2026, through May 31, 2031. This award supports research developing viral-mediated optogenetic techniques for peripheral nerve stimulation to restore motor function in patients with chronic motor injury, particularly spinal cord injury. The research will examine how light-sensitive opsins delivered via adeno-associated virus (AAV) vectors can selectively activate motor neurons in peripheral nerves to stimulate muscle activity, comparing optogenetic approaches with traditional functional electrical stimulation (FES) in rodent models of spinal cord injury. The project will deliver three key research products: (1) comparative functional assessments of optogenetic nerve stimulation versus FES in paralyzed muscle models; (2) histological characterization and mapping of motor versus sensory neuron labeling patterns following intramuscular virus injection using optimized AAV serotypes; and (3) demonstration of feasibility for chronic optogenetic stimulation of paralyzed muscles in awake, behaving animals using novel implantable nerve interfaces capable of both optical and electrical stimulation. Upon completion, the research will establish the therapeutic potential and practical utility of peripheral optogenetic nerve stimulation for motor rehabilitation applications and develop innovative tools and methodologies to advance this technology for broader peripheral nervous system applications.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $351.8k | 6/16/26 |