Project Grant R24OD037797
- The University of Mississippi was awarded a $132,062 Project Grant by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) to acquire a state-of-the-art zebrafish housing and breeding system for the university's aquatics facility. The goal is to support the expanding use of zebrafish, a critical model organism, in biomedical research at the university. The award will fund the implementation of new zebrafish culture systems, including single-sided and...
- This Project Grant award of $863,982 from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will support the development of an integrative 3D microanatomical and gene expression atlas for the zebrafish model organism. The goal is to create a comprehensive resource that will facilitate the interpretation of multi-omic data in the context of whole-organism biology and developmental stages. Key deliverables include a 3D whole-animal lifespan atlas...
- This federal Project Grant award of $779,657, funded by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351 - Research Infrastructure Programs), aims to establish and expand community-accessible resources for site-directed transgenesis in zebrafish. The University of Colorado-Denver will replace existing Tol2-based transgenes with engineered PhiC31 integrase genomic loci (PIGLET) to create the first universal landing site strains for zebrafish,...
- This $778,241 Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will support the development, characterization, and validation of recombinant antibodies and antibody-based biosensors for the zebrafish research community. The project aims to address the lack of reliable, reproducible, and molecularly defined antibodies for zebrafish proteins, which has hindered mechanistic cell biological and biochemical studies using this...
- This $173,434 Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will support the modernization and expansion of the recirculating zebrafish tanks and monitoring equipment at the University of New Mexico (UNM) Castetter Hall Animal Resource Facility. Specifically, the funding will be used to purchase: 1) six new recirculating zebrafish racks with upgraded pumps and remote monitoring capabilities, 2) upgrades to three existing...
- This federal Project Grant award of $500,000.00 from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) program supports research on the effects of elevated temperatures and pollutants on the reproductive success of zebrafish, which can serve as a model for many fish species. The study aims to investigate how environmental variables such as changes in temperature and exposure to the pollutant dioxin impact key aspects of fish reproduction, including sex ratios, gamete...
- This Project Grant award, provided by the National Science Foundation's (NSF) Biological Sciences Program (CFDA 47.074), aims to revolutionize the use of poeciliid fishes (guppies, mollies, and swordtails) as model organisms for genome editing research. The $471,066 award to Texas State University, effective September 15, 2025, through August 31, 2029, will develop new biotechnological tools to enable precise DNA editing in these small, colorful aquarium fish. This will unlock their full...
- This $1,526,917 Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) aims to revolutionize the use of poeciliid fish (guppies, mollies, and swordtails) as a model system for genome editing research. The project will develop new biotechnological tools, including immortalized cell lines and CRISPR-based DNA editing protocols, to enable precise genetic modifications in these organisms. In addition, the award will generate high-quality genome...
- This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351 - Research Infrastructure Programs) provides $194,375 to the University of Wisconsin-Madison to develop robust genome editing tools for generating floxed alleles and editing amino acid changes in the zebrafish model system. The project aims to establish a synthetic exon-mediated integration approach to reliably introduce loxP sites into target genes, enabling...
- This Project Grant award, provided by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351), will fund the modernization and improvement of the Oregon National Primate Research Center's (ONPRC) nonhuman primate reproductive biomaterial cryo-repository. The $314,402 award, made on August 15, 2025, will support the acquisition of a self-contained, automated cryogenic storage system to enhance the capabilities of the ONPRC's Assisted Reproductive...
This Project Grant award, valued at $722,774 and provided by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) under CFDA 93.351, aims to develop a new resource system to provide individual zebrafish research laboratories with decentralized capabilities for reproducible sperm cryopreservation and quality management. The project's goal is to address the urgent need to transition from the centralized sperm cryopreservation approach at the Zebrafish International Resource Center (ZIRC) to a more scalable, community-driven cryopreservation approach. This will help protect and share the valuable genetic resources of the zebrafish, which is a critical animal model used in biomedical research. The University of Oregon, as the primary awardee, will collaborate with the Aquatic Germplasm and Genetic Resources Center at Louisiana State University Agricultural Center to deliver this capability for the research community from July 2025 through June 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $722.8k | 8/11/25 |