Project Grant 2525520
- This $1,526,917 Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) aims to revolutionize the use of poeciliid fish (guppies, mollies, and swordtails) as a model system for genome editing research. The project will develop new biotechnological tools, including immortalized cell lines and CRISPR-based DNA editing protocols, to enable precise genetic modifications in these organisms. In addition, the award will generate high-quality genome...
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) project grant award of $744,781 provides funding to the University of Texas at Austin to investigate the genetic and energetic basis of mitonuclear incompatibilities during the formation of new species in swordtail fish (Xiphophorus). The research aims to identify specific combinations of mitochondrial and nuclear genes that create reproductive barriers in hybridizing populations, leading to the development of new...
- This $1,297,896 federal Project Grant award from the National Science Foundation's Biological Sciences program will support research by Texas A&M University to investigate the evolutionary and neurogenomic mechanisms underlying species discrimination and behavioral isolation in North American stream fishes. The project will integrate genomic, transcriptomic, and functional approaches to connect patterns of behavioral, neural, and genomic variation within species to the larger processes of...
- This federal Project Grant award of $432,357 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports research to understand how fishes have adapted to high-pressure environments in the deep ocean. The research aims to: Characterize patterns of genome evolution across 100 species of perciform fishes found at depths ranging from 0-8,000 meters. Measure structural changes in key biomolecules involved in metabolism, cell movement, and stress responses across...
- The National Science Foundation awarded a $138,000 Project Grant to support research titled "Parallel Genome and Phenome Evolution within and across Fish Species" from December 2021 through November 2023. The grant was awarded under the Biological Sciences program (CFDA 47.074), which aims to promote advancement in the biological sciences and strengthen the Nation's scientific enterprise through increasing knowledge and understanding of major challenges. Through this two-year award,...
- This $394,557 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) will support the "Collaborative Research: The Albatross Re-Collection Project for a Century of Genomic Change in the Tropics" at Texas A&M University-Corpus Christi. The project will analyze historical fish samples collected by the research vessel Albatross over a century ago, and compare them to modern samples, to understand how coastal fish species like the...
- This $269,173 federal Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) is funding collaborative research at Stanford University to investigate the genetic and energetic basis of mitonuclear incompatibilities during speciation in swordtail fish. The research aims to identify specific combinations of mitochondrial and nuclear genes that create reproductive barriers and impact hybrid fitness, including examining how these incompatibilities...
- This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) will support the "Collaborative Research: The Albatross Re-Collection Project for a Century of Genomic Change in the Tropics." The $343,638 award, effective July 1, 2024 through June 30, 2027, will enable researchers at Rutgers, The State University to compare historical and modern fish samples from the Philippines. The key objectives are to: 1) assemble and annotate high-quality...
- This Project Grant award of $240,000 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports a postdoctoral research fellowship focused on understanding the evolutionary consequences of genetic rescue. The project will use data from an experiment with Trinidadian guppies to investigate the genomic basis and adaptive potential of populations following genetic rescue interventions. The fellow will also lead a summer field course for undergraduates at...
- This National Science Foundation (NSF) Project Grant award under the Biological Sciences (CFDA 47.074) federal grant program provides $240,000 in funding from January 1, 2025 to December 31, 2027 to conduct research on the evolutionary dynamics of recombination landscapes and adaptive trait architectures across varying degrees of gene flow. The key research objectives are to: (1) generate multiple linkage maps to examine recombination rate as an individual-level phenotype, (2) conduct a...
This Project Grant award, provided by the National Science Foundation's (NSF) Biological Sciences Program (CFDA 47.074), aims to revolutionize the use of poeciliid fishes (guppies, mollies, and swordtails) as model organisms for genome editing research. The $471,066 award to Texas State University, effective September 15, 2025, through August 31, 2029, will develop new biotechnological tools to enable precise DNA editing in these small, colorful aquarium fish. This will unlock their full scientific potential, allowing researchers to uncover important insights into human diseases, animal behavior, and developmental biology. The project will establish immortalized cell lines, optimize transfection protocols for CRISPR-based editing, and generate high-quality genome assemblies and functional annotation resources to support downstream applications. These tools will be made publicly accessible, facilitating broader adoption of these powerful animal models in integrative organismal biology.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $471.1k | 8/1/25 |