Project Grant R24NS143946
- This federal Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to develop a closed-loop system for preventing Sudden Unexpected Death in Epilepsy (SUDEP) by regulating the functions of the dorsal raphe nucleus. The $385,091 award, effective from August 7, 2025 to July 31, 2030, will be administered by The Ohio State...
- This $400,000 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research by Baylor College of Medicine to investigate the contributions of spreading depolarization (SD) to epilepsy comorbidities and disease progression in Dravet syndrome, a major type of developmental epileptic encephalopathy. The project will leverage advanced...
- This federal Project Grant award of $414,305 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant will fund research to identify key molecules and pathways underlying the process of epileptogenesis, with the goal of developing therapies to modify disease progression. The research leverages a novel algorithm called MAGIC combined with a large...
- This Project Grant award of $129,454.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program aims to define the contributions of neuronal SUR1-TRPM4 expression to chronic seizure activity. The research will assess the effects of neuron-specific SUR1-TRPM4 overexpression on neuronal hyperexcitability in vitro and seizure susceptibility in vivo. This research, to be...
- This $579,294 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to understand the cell type-specific epigenetic mechanisms, particularly involving microRNAs, that regulate brain function and contribute to neurological disorders like epilepsy. The research aims to reveal the specific cell types and target mRNAs...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $222,160 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of California, San Diego (UCSD). The grant will support Dr. Alena Stasenko's research to develop risk and resilience models of cognitive aging in epilepsy and novel, tech-based interventions to improve brain health. The project aims to leverage digital assessment to determine the...
- This $1,309,206 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to investigate spatial recognition memory processes in patients with epilepsy. The goal is to develop improved cognitive assessments and treatments for the memory deficits commonly experienced by epilepsy patients, which are not well captured by current neuropsychological...
- This Project Grant award, titled "State-Dependent Connectivity of Impaired Autonomic Brain Networks Underlying Cardiorespiratory Dysfunction in Epilepsy", is funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $147,486 award will be used by Vanderbilt University to investigate how disruptions in neural circuits involved in cardiorespiratory and...
- This Project Grant award of $743,776 from the National Institute of Neurological Disorders and Stroke (NINDS, CFDA 93.853) supports research to determine whether and when ablating mutant cells that cause epilepsy can reverse the disease in mouse models of mTOR pathway disorders. The research aims to advance the development of AAV-mediated gene therapy approaches to treat intractable epilepsy caused by mTOR pathway mutations. This work builds upon almost two decades of the recipient...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $426,250 Project Grant under CFDA 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders, to the Regents of the University of Minnesota, Office of Sponsored Projects Administration. This 2-year grant will fund research using cutting-edge voltage imaging to examine how interactions between specific neuronal circuit elements in the hippocampus relate to the development of temporal lobe...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $528,810 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Texas Health Science Center at Houston (UTHealth) to establish the International Seizure and SUDEP Research Repository (INSSURR). This data repository will consolidate and expand upon three existing seizure and sudden unexpected death in epilepsy (SUDEP) research datasets, creating the largest publicly available resource of its kind to support research on epilepsy mortality. The project aims to overcome barriers posed by the lack of large, high-quality datasets for studying seizure mechanisms and SUDEP prevention approaches. The award has an initial term of 4 years, running from August 1, 2025 to July 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $528.8k | 7/31/25 |