Project Grant R21NS145553
- This federal Project Grant award of $458,189 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports research focused on understanding how specific membrane-remodeling factors regulate oligodendrocyte membrane dynamics and myelination in the central nervous system. The research aims to elucidate the mechanisms by which these factors shape...
- This federal Project Grant award of $440,275.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to systematically discover upstream regulators of the OLIG2 transcription factor, which plays a central role in central nervous system myelination by oligodendrocytes. The award aims to identify enhancers and transcription factors that regulate OLIG2...
- This $614,009 federal Project Grant award was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research into the molecular mechanisms of oligodendrocyte myelination and remyelination, which are critical processes for addressing demyelinating diseases of the central nervous system like multiple sclerosis. The awardee, Children's Hospital...
- The National Institutes of Health's National Institute of Neurological Disorders and Stroke awarded The Ohio State University a $119,018 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders program. This grant will support research into strategies to interrogate and enhance myelin remodeling in distal tissue after spinal cord injury. The goal of the NINDS program is to fund basic and applied research exploring the brain, nervous system structure...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $235,500.00 to Rutgers, The State University to conduct research on the role of the choline transporter CTL1 in oligodendrocyte function and myelin formation. The goal is to elucidate the mechanism by which oligodendrocytes acquire choline, an essential nutrient for myelin lipid...
- This federal Project Grant award of $427,104.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is focused on identifying biomarkers of demyelination and remyelination in a mouse model of multiple sclerosis (MS). The key objectives are to profile proteins and lipids in tissue-derived and plasma-derived extracellular vesicles to discover novel biomarkers...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded Kenyon College a Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $454,424 grant, effective April 1, 2025 through March 31, 2028, aims to characterize the cellular and molecular mechanisms of Schwann cell demyelination and identify factors that promote peripheral remyelination using a novel larval zebrafish model. The project will test...
- This federal Project Grant award of $484,125 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research conducted by Trustees of Dartmouth College to investigate how disruptions in mitochondrial dynamics within oligodendrocyte precursor cells impact their fate and the survival of mature oligodendrocytes. The research aims to provide insights into the...
- This Project Grant award of $100,272.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to understand how axon guidance is regulated in the mature nervous system. The research aims to identify molecular and cellular mechanisms that regulate axon regeneration and guidance, with a focus on using the Caenorhabditis elegans model system to study an...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $123,588 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Rutgers, The State University in New Jersey. This 2-year grant, awarded on September 1, 2025, will support research to explore the relationship between altered motor behavior and dopamine transients in the dorsolateral striatum following spinal cord injury. The research aims to establish...
This Project Grant award of $429,514 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to investigate the regulation of myelin in the adult central nervous system. The primary objectives are to: The award was granted to Rutgers, The State University of New Jersey and has a project period from September 1, 2025 to August 31, 2027. This research aims to advance the understanding of myelin plasticity and adaptation in the adult brain and spinal cord, which is important for determining how changes in myelin levels contribute to normal function and susceptibility or recovery from demyelinating events.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $429.5k | 7/30/25 |