Project Grant R21NS145550
- This federal Project Grant award of $629,796 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award aims to track, quantify, and localize key metabolic pathways that regulate brain growth during development. Specifically, the project will investigate two critical metabolic switches in the developing mouse brain: (1) a shift from glycolytic to...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,270,237 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the Icahn School of Medicine at Mount Sinai. The 5-year grant, effective August 1, 2025, will support a program to investigate the pathogenic mechanisms associated with neural disease in Congenital Disorders of Glycosylation (CDG). The program will utilize zebrafish, Drosophila, and human...
- This $563,343 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under CFDA 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders, supports research conducted by New York University (NYU) to investigate the physical, molecular, and cellular mechanisms underlying tissue guidance and tissue splitting during nervous system development. The research uses the posterior lateral line primordium migration in zebrafish as...
- This $2,503,949 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at Rockefeller University aimed at discovering therapeutic targets for neurological diseases. The project utilizes new techniques and concepts to study the fundamental mechanisms of brain disorders, focusing on how differences in cell-specific RNA regulation contribute to...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on August 1, 2025 for $1,180,687. The purpose of this 8-year project is to investigate how neural stem cell niches transition from embryonic to postnatal stages in the human forebrain, with a focus on characterizing the different neural...
- This Project Grant award, valued at $481,250.00 and provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a synthetic biological system to manipulate subcellular RNAs and proteins in growth cones or synapses of subtype- and context-specific neurons. The goal is to enable unique forms of subcellular functional investigation in subtype- and...
- This federal Project Grant award in the amount of $426,650 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The funding supports research by Trustees of Tufts College, doing business as Tufts University, to develop a hybrid strategy for efficiently deriving region-specific neural cell populations, including oligodendrocytes and neural crest progenitors,...
- This federal Project Grant award of $458,189 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports research focused on understanding how specific membrane-remodeling factors regulate oligodendrocyte membrane dynamics and myelination in the central nervous system. The research aims to elucidate the mechanisms by which these factors shape...
- This Project Grant award of $644,008.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research on the role of non-vesicular lipid transport at endoplasmic reticulum-plasma membrane (ER-PM) contact sites in phosphoinositide signaling during early dendrite development. The primary awardee is The Research Foundation For The State University Of New York, doing...
- This $649,638 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program aims to engineer alternative splicing programs to accelerate the maturation of stem cell-derived neurons. The project, conducted by The Trustees of Columbia University in the City of New York, seeks to address the critical challenge of generating mature, disease-relevant...
This $491,163.00 Project Grant award was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award supports research conducted by the Icahn School of Medicine at Mount Sinai focused on understanding the role of plasma membrane properties and cytoskeleton mechanics in regulating neuroprogenitor cell differentiation and neurogenesis during brain development. The 2-year project aims to explore how asymmetric distribution of anionic phospholipids in the plasma membrane, known as zeta potential, can influence morphological transformation and neuronal lineage commitment. The research seeks to elucidate these mechano-electrical regulation mechanisms underlying normal and dysregulated neurogenesis, which can impact neurodevelopmental disorders.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $491.2k | 7/31/25 |