Project Grant R21NS135361

This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is funding research to establish the causal roles of the dorsolateral prefrontal cortex (DLPFC) and dorsal premotor cortex (PMd) in perceptual decision-making behavior. The $436,850 award to Trustees of Boston University, doing business as Boston University Medical Campus, will be used to conduct experiments using cortical cooling deactivation techniques to temporarily silence these brain regions while monkeys perform a novel perceptual decision-making task. The goal is to determine if inactivating DLPFC or PMd differentially impacts color choice, action choice, and reaction time during the decision-making process. The award period runs from September 1, 2023 to August 31, 2025.