Project Grant R21NS143088
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $125,724 project grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on January 23, 2025. The project, titled "Hypoxia-Induced Misdirection: Understanding Postnatal Inhibitory Interneuron Migration in Neonatal Hypoxic Injury", aims to use computational approaches to identify altered...
- This $691,935 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders supports research to develop quantitative diffusion MRI methods for predicting neurodevelopmental outcomes in infants with hypoxic ischemic brain injury. The project aims to analyze diffusion MRI data from two large datasets - the High-Dose Erythropoietin for Asphyxia and Encephalopathy (HEAL)...
- This $579,294 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to understand the cell type-specific epigenetic mechanisms, particularly involving microRNAs, that regulate brain function and contribute to neurological disorders like epilepsy. The research aims to reveal the specific cell types and target mRNAs...
- This $635,386 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at Duke University to investigate the pathogenic mechanisms of inflammatory subventricular zone injury in preterm infants. The research aims to elucidate how complications of prematurity, such as intestinal perforation, can lead to diffuse myelination deficits and...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $226,112 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Colorado-Denver. The grant is focused on leveraging sex differences to understand the brain's macrophage immune response to perinatal hypoxic ischemic encephalopathy (HIE), a leading cause of death and disability in newborns. The research aims to determine the primary...
- This federal Project Grant award of $115,327.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports research to investigate the protracted maturation of cortical inhibitory neurons (CINs) in the human brain and their contribution to regional cortical specification and vulnerability during the perinatal period. The research aims to...
- This $140,400 federal Project Grant was awarded on September 1, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant aims to study the functions of lipid homeostasis during neural tube closure, a critical embryonic process for brain and spinal cord development. The research will use the FAF2 knockout mouse model to evaluate how dysregulation of lipid...
- This federal Project Grant award of $414,305 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant will fund research to identify key molecules and pathways underlying the process of epileptogenesis, with the goal of developing therapies to modify disease progression. The research leverages a novel algorithm called MAGIC combined with a large...
- This $357,191 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program aims to mechanistically link acute seizures with chronic alterations in cholinergic networks in a mouse model of Dravet syndrome. The primary objective is to delineate seizure-associated pathology in the cholinergic pedunculopontine nucleus (PPN) to identify targets for...
- This federal Project Grant award in the amount of $426,650 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The funding supports research by Trustees of Tufts College, doing business as Tufts University, to develop a hybrid strategy for efficiently deriving region-specific neural cell populations, including oligodendrocytes and neural crest progenitors,...
This $442,750 federal Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The funding supports research on the role of soluble epoxide hydrolase (SEH) inhibition in providing neuroprotection for perinatal brain injury, using a mouse model of neonatal lipopolysaccharides-sensitized hypoxia-ischemic injury. The research aims to determine if SEH inhibition, through both genetic knockout and pharmacological means, can protect neonatal mice from this type of perinatal brain injury. The grant was awarded to the University of California, Davis, which has extensive capabilities in providing specialized neuroscience and biomedical research services to federal agencies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $442.8k | 8/6/25 |