Cooperative Agreement UH3CA298962
- This Project Grant award of $162,756.00 from the National Cancer Institute (CFDA 93.398 - Cancer Research Manpower) supports research to advance understanding of chromosomal instability and radiation sensitivity in meningioma, the most common primary brain tumor. The key objectives are to: 1) Validate a transcriptomic biomarker to predict meningioma outcomes and identify patients most likely to benefit from radiation therapy; 2) Utilize novel models to define how chromosomal instability drives...
- This $5,041,790 cooperative agreement award from the National Cancer Institute (NCI), under the Cancer Centers Support Grants program (CFDA 93.397), will fund research projects at the University of California, San Francisco (UCSF) to improve cancer health disparities. The key products and services to be delivered include: Three translational cancer health disparities research projects focused on meningioma, prostate cancer, and breast cancer. The projects aim to evaluate the interplay of...
- This federal Project Grant award from the National Cancer Institute (CFDA 93.395 Cancer Treatment Research) provides $729,587.00 to The Regents of the University of California, San Francisco (UCSF) to develop and validate a personalized, voxel-wise prediction model of brain metastases risk using multi-parametric MRI imaging. The goal is to enable more targeted and tailored whole-brain radiation therapy (WBRT) that minimizes radiation exposure to healthy brain tissue, particularly in non-small...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $209,910 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on August 1, 2025. The grant supports a 2-year research project to conduct mechanistic and functional genomic analysis of genes associated with meningioma radiotherapy response. The goal is to better understand the biology of...
- This Project Grant award of $1,594,419.00 from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) is supporting research by The Regents of the University of California, San Francisco (UCSF) on "Radiopathomic Mapping of Tumor Burden for Personalized Management of IDH-Mutant Glioma." The research aims to develop innovative diagnostic and treatment approaches for a specific type of brain cancer through advanced biomedical investigations. This...
- This $421,685 federal Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) supports research conducted by the University of California, San Francisco (UCSF) to investigate the "reactive" immune system in tumors and the tumor microenvironment. The study aims to discover discrete immune cell niches within the tumor that can enhance the effectiveness of cancer immunotherapies. Using innovative spatial transcriptomics, genetic tools, and cellular...
- This $382,449 Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) supports research to develop and validate advanced dual-nuclei magnetic resonance imaging (MRI) techniques, including proton-based diffusion-relaxation correlation spectrum imaging (DR-CSI) and sodium imaging, to non-invasively differentiate between recurrent brain metastasis (RBM) and radiation necrosis (RN) in patients with brain metastases undergoing stereotactic...
- This Cooperative Agreement award from the National Cancer Institute (CFDA 93.396 Cancer Biology Research) provides $1,583,640 to the University of California, San Diego (UC San Diego) from June 23, 2025 to May 31, 2028 to advance spatial metabolomics research for cancer. The project aims to develop and apply the METASPACE open-source software platform to enable data analysis and interpretation of large, complex spatial metabolomics datasets generated through imaging mass spectrometry techniques....
- This Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides $655,306 to The Regents of the University of California, San Francisco (UCSF) to develop and evaluate a therapeutic strategy that combines a brain-penetrant glyoxalase 1 (GLO1) inhibitor with radiation for the treatment of isocitrate dehydrogenase-mutant (IDHm) gliomas, one of the deadliest forms of brain cancer. The project aims to mechanistically validate reactive metabolite...
- The National Cancer Institute (NCI) has awarded a $572,490 Project Grant to The Regents of the University of California, San Francisco (UCSF) under the federal Cancer Detection and Diagnosis Research program (CFDA 93.394). The project, titled "PILLAR: Multi-Modal Imaging AI Models for Breast Cancer Risk", aims to develop an AI-powered tool to predict breast cancer risk using longitudinal data from mammograms, tomosynthesis, and MRI scans. The goal is to create more accurate cancer risk...
This Cooperative Agreement, awarded by the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research), provides $315,066 in funding to The Regents of the University of California, San Francisco (UCSF) from September 1, 2025 to August 31, 2028. The project aims to validate, translate, and clinically implement a gene expression biomarker to predict outcomes and radiotherapy responses for meningioma, a common type of brain tumor. The research will focus on improving risk stratification and treatment selection for meningioma patients, as current treatment approaches have significant limitations. The award supports UCSF's specialized expertise in cancer research, biomarker development, and clinical translation to address these unmet needs in meningioma management.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $315.1k | 8/15/25 |