Project Grant R21NS140900
- This $407,538 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports research and development of a novel optical neuroimaging technology called Diffuse Correlation Spectroscopy (DCS) at Duke University. The goal is to enable deep tissue measurement of blood flow within the brain, which can provide valuable insights into neurological and mental health conditions. The project aims to develop a parallelized DCS system using single-photon...
- This federal Project Grant award, valued at $492,749.00 and awarded by the National Institute of Neurological Disorders and Stroke (NINDS), supports the development of a novel non-invasive magnetic resonance imaging (MRI) technique called ratiometric dual contrast (RDUAL) pH-weighted MRI. The goal is to create an imaging tool that can accurately map the ischemic penumbra (tissue at risk of infarction) and evaluate the risk of reperfusion injury in acute ischemic stroke patients. This research,...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $373,778 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Research Foundation For The State University Of New York (Stony Brook University) to establish a novel vasculature database and analytical platform for mouse brain vasculature. The project aims to develop topology-preserving vessel segmentation algorithms and advanced statistical models...
- This federal Project Grant award of $664,458, provided by the National Institute of Neurological Disorders and Stroke (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders), supports research to develop a novel non-invasive optical imaging technique for the prehospital detection of large vessel occlusion (LVO) in acute stroke patients. The University of Pennsylvania, the grant recipient, is validating this optical cerebral hemodynamic monitoring approach...
- This federal Project Grant award of $770,502.00, awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to understand the molecular mechanisms by which collagen IV regulates TGF-beta signaling and its role in cerebral small vessel disease (CSVD). The research will use mouse models to perform intravital imaging of the cerebral vasculature and...
- This federal Project Grant award, provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), supports the development of an advanced interferometric diffuse optics (IDO) system to quantitatively and specifically measure cerebral blood flow after subarachnoid hemorrhage (SAH). The $1,244,260 award to New York University aims to create a novel 1064 nm IDO...
- This federal Project Grant award of $486,110 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will support advanced research at the University of Minnesota. The project aims to use cutting-edge optical imaging techniques like three-photon imaging, two-photon optogenetics, and two-photon photothrombosis to precisely map neurovascular coupling - the link between...
- This Project Grant award of $596,570.00 from the National Institute of Neurological Disorders and Stroke (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) will support research by Vanderbilt University to develop and validate improved methods for sub-voxel fiber identification and tissue characterization using diffusion magnetic resonance imaging (dMRI). The research aims to quantify and improve the reliability of sub-voxel measurements of fiber...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $147,486 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the Massachusetts Institute of Technology (MIT) from July 1, 2025 to June 30, 2027. The grant funds the development of a novel Magnetic Resonance Imaging (MRI) method to concurrently measure brain tissue displacement, blood dynamics, and cerebrospinal fluid (CSF) flow in humans. This research...
- This federal Project Grant award of $578,701, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to develop a new high-speed 3D voltage imaging microscopy system capable of capturing real-time neuronal activity over extended periods. The research, conducted by the University of California, Los Angeles (UCLA), aims to overcome the limitations...
This $234,750 Project Grant award from the National Institute of Neurological Disorders and Stroke (CFDA 93.853) supports research at Emory University in Georgia focused on developing an instantaneous digital subtraction angiography (IDSA) technique for neurovascular applications. The research aims to overcome key clinical challenges associated with current intra-arterial digital subtraction angiography (IA-DSA) procedures, such as motion artifacts, risk of complications, and contrast-induced nephropathy. The project will explore the use of x-ray phase-sensitive imaging and super-paramagnetic iron oxide nanorods to enable a minimally invasive, intravenous DSA (IV-DSA) alternative for improved diagnosis and treatment of cerebrovascular diseases. The award period runs from August 1, 2025 to July 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $234.8k | 7/29/25 |