This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $2,370,000 to develop advanced human pluripotent stem cell (HPSC) tools to create comprehensive and region-specific models for studying pain circuitry. The primary objectives are to: Develop scalable methods to generate region-specific sensory neurons and glial subtypes, Create and characterize region-specific...
This Project Grant award, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, aims to develop enhanced genetic targeting methods for specific neuronal populations. The $689,689 award to the Trustees of Tufts College (Tufts University School of Medicine) will fund the design and evaluation of miniaturized enhancer-splicing linked expression design...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $397,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program to the Massachusetts Institute of Technology (MIT). The grant, effective May 1, 2025 through April 30, 2030, will support innovative research to study fundamental principles linking neurodevelopmental processes to the functional organization of neural circuits. The goal is to...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, provides $147,656.00 to Duke University to conduct research on human-specific splicing regulation in neurogenesis and disease. The key products and services to be delivered under this award include: 1) Testing the function of intronic human-specific sequences to enhance and...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, provides $221,120.00 to the University of Texas Health Science Center at Houston (UTHealth) to conduct research on improving neural progenitor cell survival and migration in the context of neurodegenerative diseases and brain injuries, such as stroke. The research investigates...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $1,282,359.00 to the Regents of the University of Michigan to conduct research on the regulation of intermediate progenitor cells during neural development. The project aims to define the mechanisms that control the competency of neural stem cells to generate intermediate...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $563,343 Project Grant (R01NS140233) to New York University School of Medicine under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The grant supports research focused on understanding how tissues move and split to form neural cell clusters and layers during nervous system development. The researchers aim to use the zebrafish posterior lateral...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support the development of a novel human stem cell-derived multi-cellular model to study the developmental processes underlying the spinal cord midline crossing of axons. The $598,952 award, with a project period from December 1, 2024 to November 30, 2029, will enable the...
This $458,189 Project Grant, awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, funds research to investigate the role of membrane-remodeling factors in regulating oligodendrocyte morphology and myelination in the central nervous system. The research aims to: (1) identify the expression and sufficiency of membrane-remodeling factors in...
The Trustees of Columbia University in the City of New York (Columbia University), through its Health Sciences Division, was awarded a $445,009 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The grant's objective is to develop approaches for introducing developmentally-relevant inputs and reading out neuronal activity in human brain organoids to...