Project Grant R21NS131829

Award Date 9/21/23
Completion Date 8/31/25
Dollars Obligated $413K
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
New Orleans, LA 70112, USA
Similar Awards
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, provides $225,000.00 to Louisiana State University Health Sciences Center New Orleans to support research on how mutations in the PPP2R5C and PPP2R5D genes, which encode B56 regulatory subunits of the PP2A phosphatase complex, affect synaptic development, neural activity,...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded Brandeis University a $846,469 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The goal of this 2-year project is to elucidate how the ESCRT (Endosomal Sorting Complex Required for Transport) machinery is regulated and deployed in neurons. The research aims to develop new visualization and manipulation tools to study ESCRT dynamics in...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to investigate the regulation of presynaptic gene transcripts during synaptogenesis. The $145,642 award to Albert Einstein College of Medicine, spanning September 1, 2024 to June 30, 2027, will leverage advanced imaging techniques and mass spectrometry to...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $644,008 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to The Research Foundation For The State University Of New York, doing business as Stony Brook University. The grant, awarded on February 21, 2025, supports research investigating the role of non-vesicular lipid transport at endoplasmic reticulum-plasma membrane (ER-PM) contact sites in phosphoinositide...
This Project Grant award of $1,271,040.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) supports innovative research at Rockefeller University aimed at discovering new therapeutic targets for neurological diseases. The key products and services to be delivered include: Developing and validating new model systems to enable unexpected discoveries about the...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $404,340 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Georgia Research Foundation, Inc. The project aims to develop a novel method using split fluorescent protein tags to map the localization of neurotransmitter receptors within neural circuits in the Drosophila model organism. This work will provide crucial new insights into the...
This federal Project Grant award of $434,225.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research at Rosalind Franklin University of Medicine & Science to investigate the homeostatic regulation of Cav2 voltage-gated calcium channels and their role in synaptic plasticity. The research aims to elucidate the mechanisms by which synaptic vesicle...
This federal Project Grant award, valued at $444,599.00 and awarded by the National Institute of Neurological Disorders and Stroke (NINDS), supports research under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The research aims to investigate the impact of neuronal activity on oligodendrocyte progenitor cell proliferation, survival, and differentiation in the corpus callosum and cortex. The project will use designer receptors...
This $402,813 Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), supports research aimed at investigating the reciprocal interactions between neural circuit architecture and synaptic function in the hippocampus. The research will utilize large-scale in vivo electrophysiology and optical labeling techniques to: 1)...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research focused on understanding the dynamic properties of mossy fiber synapses in the hippocampus and their role in spatial pattern separation. The $880,000 grant, awarded to Northwestern University for the period of August 1, 2024 to July 31, 2026, aims to test how the...

This $412,500 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders federal grant program (CFDA 93.853), supports research conducted by Louisiana State University Health Sciences Center New Orleans. The research aims to define the roles of the protein Coracle in regulating the dynamics of active zones - specialized structures in nerve terminals that control neurotransmitter release. Specifically, the project will investigate how the dephosphorylation of Coracle by the WRD phosphatase affects synaptic stability and cognitive function. The research findings could provide insights into the molecular mechanisms underlying structural neuroplasticity and its implications for learning and memory. The award period runs from September 21, 2023 to August 31, 2025.

Generated 8/13/24, 10:10 AM