This $537,508 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support research to understand the role of endogenous zinc protoporphyrin (ZnPP) in intracerebral hemorrhage (ICH)-induced brain damage. The research aims to elucidate the mechanisms by which ICH triggers ZnPP formation and how ZnPP contributes to neurotoxicity, as well as evaluate...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $426,250 Project Grant under CFDA 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders, to the Regents of the University of Minnesota, Office of Sponsored Projects Administration. This 2-year grant will fund research using cutting-edge voltage imaging to examine how interactions between specific neuronal circuit elements in the hippocampus relate to the development of temporal lobe...
The University of Georgia Research Foundation, Inc. (UGA Research Foundation) was awarded a $379,171 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports a 2-year research project to investigate cerebrovascular dysfunction and cerebral atrophy in severe traumatic brain injury (STBI). Specifically, the project aims to: 1) Characterize...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $628,133 Project Grant (CFDA 93.853) to Rutgers, The State University to study the "Metabolic Mechanisms of Recovery in Mild TBI" from September 1, 2024 to July 31, 2028. The research aims to determine if activating the CYPIN protein can promote functional recovery after mild traumatic brain injury (TBI) in mice. This builds on previous work identifying CYPIN as a key molecule regulating methionine levels and...
This federal Project Grant award of $657,958, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to elucidate the cellular and network mechanisms underlying epileptic activity and seizures, as well as investigate the neuronal impact of neurostimulation for treating drug-resistant epilepsy. The 5-year award to Trustees of Boston University...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the effects of pediatric traumatic brain injury (PTBI) and early life stress on the development of the prefrontal cortex and resulting cognitive function. The $148,700 award to The Ohio State University aims to define acute neuroimmune changes in the...
This $648,893 Project Grant, awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will fund research to investigate spatial recognition memory and its relationship to cognitive deficits in epilepsy patients. The University of California, Davis will use a novel paradigm with photorealistic dynamic scenes to assess familiarity, recollection, and memory...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will fund research at the Augusta University Research Institute, Inc. (doing business as Georgia Health Sciences) to investigate the mechanisms linking traumatic brain injury (TBI) to subsequent neurodegeneration and dementia. The $1,975,262 award will support a 3-year study...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $423,500 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to the Augusta University Research Institute, Inc. The objective is to develop and evaluate engineered exosomes carrying neuron-targeting peptides and a therapeutic protein (neuroglobin) for treating ischemic stroke. The research will: 1) characterize the engineered exosomes and assess their...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $102,948.00 to Case Western Reserve University to investigate the link between traumatic brain injury (TBI), hematopoietic stem cell dysfunction, chronic neurodegeneration, and Alzheimer's disease (AD). The key objectives are to assess how acute TBI induces changes to...