Project Grant R21HD118426
- This Project Grant award of $761,367, provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to determine whether biomarkers in fetal central nervous system-derived extracellular vesicles can predict derangements in fetal neurodevelopment in women using cannabinoids during pregnancy. The 5-year project, which began on September 1, 2025, will partner with an ongoing NIH-funded clinical cohort of 450 subjects to identify novel...
- This $616,372 federal Project Grant was awarded on July 15, 2025 by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The grant supports research to identify neuronal, glial, and neural stem/progenitor cell transposable element (TE) transcriptional and epigenetic gene regulatory states involved in SIV, antiretroviral therapy, and cannabinoid exposure in a non-human primate model. Additionally, the research aims to identify TE expression...
- This federal Project Grant award, funded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), supports research on the impact of oral THC consumption during adolescence on the adult mouse brain. The $716,455 award, effective July 1, 2025 through March 31, 2030, will enable researchers at the University of Washington to: Determine how long-term adolescent use of THC-gelatin, alone or in combination with cannabidiol (CBD), impacts...
- This $1,336,938 Project Grant, awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), supports research on the impact of chronic prenatal THC exposure on SIV-associated inflammation and impairments in placental and fetal development. The grant was awarded to Tulane University, a private non-profit research university, to conduct this 5-year (September 1, 2025 to May 31, 2030) research project. The goal is to define the...
- This federal Project Grant award, totaling $119,084, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The primary objective of this 2-year project (7/15/2025 - 6/30/2027) is to quantify the risk of congenital malformations in infants associated with in utero exposure during the first trimester to certain cardiometabolic medications, including angiotensin-converting enzyme...
- This Project Grant award, titled "LONGITUDINAL EFFECTS OF PRENATAL CANNABIS AND TOBACCO CO-EXPOSURE AND POSTNATAL ADVERSITY ON CHILD REGULATION: THE BUFFERING ROLE OF SENSITIVE PARENTING," is funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), under CFDA Program 93.279 - Drug Use and Addiction Research Programs. The $149,000 grant will be awarded to the University of Oregon to conduct a secondary analysis of a longitudinal study...
- This $288,000 Project Grant was awarded on August 4, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research federal grant program (CFDA 93.865). The grant supports research conducted by the Van Andel Research Institute in Grand Rapids, Michigan to investigate fatty acid metabolism and identify potential therapeutic targets for treating mitochondrial fatty acid synthesis (MTFAS)...
- This $160,056 Project Grant awarded by the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to optimize antibiotic use and improve understanding of developmental pharmacokinetics in newborn infants. The key objectives are to: (1) quantify maternal antibiotic concentrations (ampicillin, gentamicin, vancomycin, clindamycin) in maternal and umbilical cord blood; and (2) perform...
- This $293,550 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), is funding research to investigate the effect of inherited maternal cells on BCG-specific T cell responses in HIV-exposed and unexposed infants. The award supports a study hypothesizing that reduced transmission of maternal microchimerism in utero may be a mechanism...
- This $507,000.00 federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports research at the Icahn School of Medicine at Mount Sinai to investigate the epigenetic mechanisms underlying cannabis use disorder. The project, running from September 1, 2025 to May 31, 2030, aims to leverage a translational animal model of voluntary THC consumption to study sex differences and individual variability in...
This $420,750 Project Grant was awarded on September 9, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research Program (CFDA 93.865). The grant is funding research at Washington State University aimed at evaluating the effects of certain drugs (acetaminophen, valproic acid, amoxicillin-clavulanate, cannabidiol, and isoniazid) on liver toxicity markers in a human hepatocyte model. The research will leverage hepatocytes from pediatric and adult donors to understand age-specific mechanisms of drug-induced liver injury (DILI) in children. The study will analyze proteomic, metabolomic, and extracellular vesicle biomarkers to identify molecular changes and drug-protein adducts, which will then be integrated into quantitative systems toxicology models to predict DILI pathways and mechanisms. The ultimate goal is to develop improved methods for mitigating the risk of DILI in children, which is crucial for ensuring the safety of pediatric medications.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $420.8k | 9/9/25 |