This Project Grant award of $274,595.00 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support research at Emma Pendleton Bradley Hospital, a non-profit psychiatric hospital, to investigate the biological mechanisms linking childhood adversity and accelerated aging. The research aims to explore how early life stress, including childhood maltreatment and trauma, may alter mitochondrial DNA and function, potentially contributing to increased risk for stress-related and age-related health conditions such as psychiatric disorders, obesity, diabetes, and cardiovascular disease. The project leverages longitudinal data and biospecimens from an existing study on childhood maltreatment to provide insight into the biological underpinnings of adversity-related risks for accelerated aging and disease development. Findings from this research are expected to inform new treatment and prevention approaches targeting these mechanisms.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | ($14k) | 9/10/24 | ||
| Not listed | $289.0k | 9/4/24 |