The National Institute of Child Health and Human Development (NICHD) awarded a Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. The $364,324 grant, awarded on August 15, 2024, will fund research to investigate the role of retrotransposable elements (RTEs) in neurodevelopment and their potential involvement in neurodevelopmental disorders. The research aims to...
This $2,004,633 Project Grant, awarded on September 17, 2024 by the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 Child Health and Human Development Extramural Research, supports research on dysregulated RNA metabolism and its role in maternal diabetes-induced neural tube defects (NTDs). The research aims to determine how maternal diabetes represses miR-322 expression, upregulates the RNA binding protein RBM47, and stabilizes the long non-coding RNA NEAT1,...
The National Institute of Child Health and Human Development (NICHD) awarded a $431,750 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Rutgers, The State University of New Jersey, to investigate how the cytokine interleukin-6 (IL-6) affects the proliferation, specification and gene expression of human and mouse secondary neural progenitor cells. The goal is to establish IL-6 as a key target for intervention to prevent neurodevelopmental disorders like...
This federal Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $216,000.00 to the University of California, San Diego (UCSD) to elucidate the function of CTCF, a key protein involved in chromatin organization, in neural differentiation and neurodevelopment. The research will employ both 2D and 3D human cell models to examine the role...
This $709,362 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support research by New York University School of Medicine to investigate the neural circuits underlying infant-directed behaviors, including both caregiving and hostile behaviors, in mice. The research aims to elucidate the specific neural populations and pathways involved in these behaviors,...
This Project Grant award of $294,408.00 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support research by Emory University to investigate the impact of coding and non-coding mutations in the ARID1B gene on neuronal development. The project aims to characterize ARID1B haploinsufficient mice at the single-cell level to identify patterns of dysregulation to chromatin accessibility...
This federal Project Grant award, funded by the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 Child Health and Human Development Extramural Research program, supports research to elucidate the epigenetic mechanisms underlying growth and neurodevelopmental disorders, specifically Weaver and Sotos syndromes. The $674,312 award to The Johns Hopkins University will establish mouse and human cell models to study the neurological, skeletal, and transcriptional...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 - Child Health and Human Development Extramural Research, totaling $309,496, will fund research at Duke University to investigate the role of gene regulatory networks in neonatal nutrition and immunity. The key objectives of this 2-year project are to: 1) leverage bioinformatic analysis and genetic mouse models to define the gene regulatory networks controlled by the transcription...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will fund research to investigate the role of miRNA-mediated buffering mechanisms in mediating gene-environment interactions and contributing to structural birth defects in 22q11.2 Deletion Syndrome (22q11DS). The $773,500 award, effective July 17, 2024 through June 30, 2026, will be provided to the...
The National Institute of Child Health and Human Development (NICHD) awarded a $237,030 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to New York University School of Medicine to conduct a longitudinal assessment of human brain connectome changes across the birth transition in both term and preterm pregnancies. The project aims to explore critical developmental processes, medical conditions, and health outcomes affecting infants, children, and young adults....