The National Institute of Child Health and Human Development (NICHD) awarded a $148,568 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Colorado-Denver. The grant, effective February 1, 2025 through July 31, 2026, supports research to identify the mechanisms by which fetal glucagon regulates placental nutrient delivery and uterine blood flow. Key objectives include establishing how fetal glucagon inhibits placental...
This Project Grant award, valued at $1,454,109 and running from July 1, 2024 to April 30, 2029, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports research to investigate the physiological and genetic mechanisms underlying placental responses to hypoxia and their impact on fetal growth and development. The key research activities include: Generating cell...
This federal Project Grant award, totaling $429,000.00 and granted by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to assess placental vascularization development using contrast-enhanced ultrasound (CEUS) imaging. The research aims to determine if the SHAPE (Subharmonic Aided Pressure Estimation) technique can serve as a safe, noninvasive, and real-time tool to...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $234,000.00 to The Regents of the University of Colorado, doing business as the University of Colorado-Denver, to conduct research on a novel NF-kB genetic variant associated with preeclampsia, a serious pregnancy complication. The key objectives are to: Establish if the NF-kB variant is linked...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to develop non-invasive magnetic resonance imaging (MRI) techniques for early diagnosis and prediction of fetal growth restriction (FGR) during pregnancy. The $295,212 award will be used by the University of South Australia to conduct a series of predictive MRI scans in a sheep...
This $248,999 federal Project Grant award, funded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to identify effective therapeutic agents for managing infection-induced preterm labor (III-PTL). The primary objectives are to: 1) Optimize a high-throughput screening assay to measure changes in proinflammatory cytokines released from pathogen-associated molecular...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), funds the development and validation of a machine learning-based fetal monitoring system to predict and prevent fetal hypoxia. The $261,310 award will support the creation of a high-sensitivity, high-specificity predictive model using a multi-site dataset of 50,000 fetal monitoring tracings coupled with...
This Project Grant award of $2,018,716, issued on June 25, 2024 by the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research), supports research on the mechanisms of uterine fluid absorption during early pregnancy. The research aims to comprehensively investigate the hormonal and ionic regulation of uterine fluid movement, with a focus on elucidating the roles of estrogen receptor alpha (ERA) and progesterone receptor...
The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) is focused on developing and testing an innovative approach to reduce inflammation-associated preterm birth. The $635,254 award to the University of Texas Medical Branch at Galveston will fund research to evaluate the safety, stability, and efficacy of extracellular vesicle-mediated delivery of the...