The National Institutes of Health (NIH) Office of the Director has awarded a $2,927,457 Cooperative Agreement grant under the Trans-NIH Research Support program (CFDA 93.310) to The Washington University to conduct the "Infant Down Syndrome Brain and Behavior Study". The goal is to collect multimodal neuroimaging data, developmental behavioral assessments, and social communication measures on a cohort of 100 infants with Down syndrome and 50 typically developing controls at ages 6, 12,...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under CFDA Program 93.865 - Child Health and Human Development Extramural Research, aims to investigate the role of corticolimbic brain circuits in regulating maternal behavior and threat/stress responses during the postpartum period. With total funding of $534,004 over the project period from August 1, 2024 to July 31, 2029, the research will utilize genetic technologies, neural circuit...
The National Institute of Child Health and Human Development (NICHD) awarded a $545,450 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to the Albert Einstein College of Medicine in Bronx, NY. The award, which runs from August 8, 2024 to May 31, 2029, will support research into the neural circuits and molecular mechanisms underlying adaptive infant-directed behavior in mice, with a focus on understanding how hypothalamic microcircuits coordinate parental...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to investigate the neural circuits underlying infant-directed behaviors in mice. The $709,362 award to New York University School of Medicine aims to elucidate the role of specific cell populations in the brain that drive both parental care and infanticidal behaviors. The project will...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under CFDA program 93.242 Mental Health Research Grants provides $176,638 to The Washington University in St. Louis to investigate how unpredictability in parental emotional behavior during infancy impacts the development of emotion regulation and brain function in young children, and how these factors contribute to risk for childhood psychopathology. The proposed research leverages an ongoing longitudinal study...
This federal Project Grant award for $621,292, issued on August 14, 2024 by the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 Child Health and Human Development Extramural Research, will support research to disentangle the relative contributions of sleep stage and age in early brain network development. The primary recipient, The Washington University in St. Louis, will conduct concurrent electroencephalogram (EEG) - functional magnetic resonance imaging...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $565,246 in funding to Washington State University to conduct research on the effects of maternal obesity and exercise on hippocampal synapse development. The key objectives of the research are to determine how insulin, apelin, irisin, and BDNF signaling pathways mediate the positive and...
The National Institute of Child Health and Human Development (NICHD) awarded a $237,030 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to New York University (NYU) School of Medicine on August 1, 2024. The grant will fund a longitudinal assessment of changes in the human brain connectome across the birth transition in both term and preterm pregnancies. The research, to be completed by July 31, 2026, aims to enhance the scientific understanding of critical...
This federal Project Grant award of $418,178 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to provide mechanistic insights into the neurobiological mechanisms by which maternal sensitivity is compromised by postpartum depression. Specifically, the University of Massachusetts (UMass), through its Office of Grant & Contract Administration, will use intersectional viral...
This National Science Foundation (NSF) Project Grant award under the Biological Sciences program (CFDA 47.074) provides $552,000 in funding to Michigan State University to study how the maternal brain changes across pregnancy and early postpartum to promote the positive perception of infant touch. The project will investigate the neural basis of maternal receptivity to offspring touch, with a focus on the role of cortical perineuronal nets (PNNs) in the primary somatosensory cortex and insular...
The National Institutes of Health (NIH) Office of the Director awarded Washington State University a $138,097 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) on June 3, 2022. The grant will fund a study examining the effects of mother-infant brain activity coordination on emerging self-regulation by testing the synchronization hypothesis. Researchers will study the extent of neural synchronization between mothers and infants during a regulatory challenge task known as the Still Face Paradigm. The study aims to ascertain associations between greater synchronization, concurrent infant regulation, and the quality of maternal caregiving. Assessments of 100 mother-infant pairs beginning at 6 months of age will continue at 9 and 12 months to examine infant regulatory development. Results will inform preventative efforts to capitalize on maternal caregiving and be disseminated to parents and providers.